{"id":"W2900877533","doi":"10.1101/mcs.a003137","title":"Whole-genome and transcriptome profiling of a metastatic thyroid-like follicular renal cell carcinoma","year":2018,"lang":"en","type":"article","venue":"Molecular Case Studies","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia; BC Cancer Agency; Canada's Michael Smith Genome Sciences Centre; Vancouver General Hospital; Abbotsford Veterinary Clinic","funders":"BC Cancer Foundation; University of British Columbia; Canada Research Chairs; Genome British Columbia; Michael Smith Health Research BC; Canadian Institutes of Health Research; Genome Canada","keywords":"PDGFRB; PDGFRA; Transcriptome; Cancer research; Biology; Medicine; Oncology; Genetics; Gene; Gene expression; Stromal cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002175009,0.000321919,0.0006996126,0.0001845555,0.000138849,0.0000121708,0.00005674829,0.0000477229,0.000009715339],"category_scores_gemma":[0.00004140146,0.0002510221,0.0002168662,0.0002589466,0.0004170015,0.00004667366,0.00008323851,0.000122661,0.00001212401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008178816,"about_ca_system_score_gemma":0.00006423683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005171857,"about_ca_topic_score_gemma":0.00001182768,"domain_scores_codex":[0.9983189,0.0001034517,0.0004094606,0.0004636967,0.0003506964,0.0003537837],"domain_scores_gemma":[0.9989368,0.00004205921,0.0001160368,0.000421703,0.0003194579,0.0001638995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00018101,0.0001526884,0.0008241113,0.0006243646,0.0007312383,0.03387714,0.002662467,0.000003471533,0.9606926,0.00004389096,0.00005829193,0.0001486603],"study_design_scores_gemma":[0.004491149,0.004282147,0.001810731,0.0001015505,0.002742683,0.009382174,0.003852486,0.00008208016,0.9720228,0.0001197078,0.000736178,0.0003762735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604615,0.0372363,0.0005289274,0.0001795362,0.00007558541,0.0007766176,0.00004533747,0.00003099504,0.0006651845],"genre_scores_gemma":[0.993069,0.00008402111,0.00620782,0.0001860194,0.00006016852,0.00007253597,0.00002418454,0.00004444152,0.0002518333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03715227,"threshold_uncertainty_score":0.9999942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03151225445667651,"score_gpt":0.2825513771382582,"score_spread":0.2510391226815817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}