{"id":"W2900900438","doi":"10.1002/jcp.27527","title":"PINK1/Parkin‐mediated mitophagy promotes apelin‐13‐induced vascular smooth muscle cell proliferation by AMPKα and exacerbates atherosclerotic lesions","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"National Natural Science Foundation of China","keywords":"Mitophagy; Apelin; AMPK; Parkin; Vascular smooth muscle; PINK1; Cell biology; Endocrinology; Autophagy; Internal medicine; Cell growth; Chemistry; Biology; Medicine; Receptor; Protein kinase A; Apoptosis; Kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002213056,0.0003656217,0.0004617322,0.0003207784,0.0002338625,0.0002877616,0.0001534817,0.0002798743,0.001142038],"category_scores_gemma":[0.0001151079,0.0002087238,0.0004063313,0.0001712027,0.000287171,0.0002593496,0.000361673,0.0008704889,0.0002334183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001925647,"about_ca_system_score_gemma":0.0001830167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002703838,"about_ca_topic_score_gemma":0.0004553801,"domain_scores_codex":[0.9997965,0.00003678683,0.00002721747,0.00003874423,0.00004069633,0.00006022029],"domain_scores_gemma":[0.9998575,0.000009366112,0.00005015373,0.00001329003,0.00001402253,0.00005558817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008978021,0.00009664482,0.0005323494,0.0001066212,0.00001954098,0.000240525,0.00003671562,0.00004266449,0.9963892,0.00006072041,0.00005825725,0.001518958],"study_design_scores_gemma":[0.0001408992,0.001926862,0.04056109,0.00003297162,0.0001021882,0.001221995,0.0001933576,0.00148127,0.951153,0.0001825791,0.002990153,0.00001356931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964727,0.001461489,0.001192558,0.0001216306,0.00002940021,0.00001933973,0.0001228008,0.00004351605,0.0005367419],"genre_scores_gemma":[0.9957857,0.001073288,0.001011943,0.00009885281,0.00001809797,0.00004579392,0.0002114344,0.00001090224,0.001744034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142038,"threshold_uncertainty_score":0.003820479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01843879742212572,"score_gpt":0.2701223670863617,"score_spread":0.251683569664236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}