{"id":"W2900932809","doi":"10.2147/jpr.s177967","title":"Penetration and efficacy of transdermal NSAIDs in a model of acute joint inflammation","year":2018,"lang":"en","type":"article","venue":"Journal of Pain Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Atlantic Veterinary College","keywords":"Medicine; Celecoxib; Ibuprofen; Transdermal; Pharmacology; Inflammation; Drug; Adverse effect; Anesthesia; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008637893,0.00006313661,0.0003005259,0.0006278973,0.00002798106,0.000006538398,0.00006081018,0.00008642287,0.00002422505],"category_scores_gemma":[0.0007778076,0.00004841763,0.00006706361,0.0002681525,0.0001900733,0.0001226711,0.00001454867,0.0003461525,9.598762e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000050762,"about_ca_system_score_gemma":0.0003183749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001501351,"about_ca_topic_score_gemma":0.00001602659,"domain_scores_codex":[0.9980133,0.0004483764,0.0005882762,0.00007478068,0.0007020769,0.000173232],"domain_scores_gemma":[0.9985818,0.0003025857,0.000187503,0.0001062287,0.0007150483,0.0001068551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00197964,0.0001616009,0.01104544,0.0005131431,0.00009147587,0.00005731652,0.003778243,0.0001672728,0.9666708,0.000180465,0.0003521096,0.01500255],"study_design_scores_gemma":[0.008076916,0.006638521,0.2090433,0.001299,0.0001032793,0.00008599975,0.0003287835,0.1612243,0.6123446,0.0006425433,0.00009913259,0.0001136125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967749,0.0001026228,0.002215099,0.0004307202,0.00003115408,0.0002458097,0.000001508863,0.000001665199,0.0001965571],"genre_scores_gemma":[0.9983724,0.0001282312,0.001211339,0.00001255307,0.0002303281,0.000002157075,0.000001286674,0.000008187321,0.00003348733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3543262,"threshold_uncertainty_score":0.2993739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06843269143938048,"score_gpt":0.3774756928816357,"score_spread":0.3090430014422552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}