{"id":"W2900940789","doi":"10.1016/j.tiv.2018.11.004","title":"Bromelain with peroxidase from pineapple are more potent to target leukemia growth inhibition - A comparison with only bromelain","year":2018,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Pineapple and bromelain studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Ministry of Defence","keywords":"Bromelain; Apoptosis; Myeloid leukemia; Cytochrome c; Intracellular; Cell cycle; Cell growth; Cell culture; Caspase; Biology; Annexin; Cancer research; Peroxidase; Cancer cell; Leukemia; Molecular biology; Cancer; Biochemistry; Programmed cell death; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202997,0.0004227615,0.0002295886,0.0001997646,0.0001571928,0.0002289909,0.0001893137,0.000234097,0.001645489],"category_scores_gemma":[0.0001199978,0.0001266804,0.0002421733,0.0001666428,0.0001982426,0.0003325513,0.0001420322,0.0004923043,0.0002965426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00016238,"about_ca_system_score_gemma":0.0002318851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001031792,"about_ca_topic_score_gemma":0.001172783,"domain_scores_codex":[0.9998721,0.00002838368,0.000006986601,0.00002703791,0.00002812865,0.00003727265],"domain_scores_gemma":[0.9999048,0.00003095764,0.00001363431,0.0000146005,0.00001377928,0.00002230829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000151356,0.00003928024,0.0001195662,0.00002168945,0.000004641168,0.00002077268,0.00001124896,0.00003357127,0.9988257,0.00003557579,0.0000147126,0.0007219253],"study_design_scores_gemma":[0.000003767454,0.0003783823,0.001151185,9.815645e-7,0.000008249447,0.00006693823,0.00001062917,0.00004912269,0.9976661,0.000008562897,0.0006551653,9.254087e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991533,0.002551751,0.002713856,0.00004765409,0.00002962117,0.00003388478,0.0001970393,0.00006090507,0.002832155],"genre_scores_gemma":[0.9923022,0.0009373617,0.001618175,0.00002689295,0.000009928211,0.00001596874,0.0004768058,0.00001925662,0.004593498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001645489,"threshold_uncertainty_score":0.005504668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008514797259663892,"score_gpt":0.2455281213117152,"score_spread":0.2370133240520513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}