{"id":"W2901054298","doi":"10.1371/journal.pcbi.1006549","title":"Simulations of blood as a suspension predicts a depth dependent hematocrit in the circulation throughout the cerebral cortex","year":2018,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Science Foundation","keywords":"Cerebral blood flow; Neuroscience; Microcirculation; Blood flow; Cerebral cortex; Hematocrit; Cerebral circulation; Hemodynamics; Circle of Willis; Anatomy; Neurovascular bundle; Computer science; Cardiology; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116768,0.0001025296,0.0001438573,0.00006922815,0.0002856105,0.00001708089,0.000193716,0.00005840042,0.00006739915],"category_scores_gemma":[0.0004090219,0.00005927641,0.0000408479,0.0002753193,0.0003820127,0.00006971465,0.00007055628,0.00012375,0.00002777406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001037756,"about_ca_system_score_gemma":0.00005497586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003229915,"about_ca_topic_score_gemma":0.0001042983,"domain_scores_codex":[0.9987878,0.0002772108,0.0002842445,0.0002607588,0.0002378337,0.0001522144],"domain_scores_gemma":[0.9984235,0.001140841,0.0001330437,0.0001616544,0.0001229466,0.00001808166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"observational","study_design_scores_codex":[0.0003615133,0.0008674422,0.2029054,0.00005037755,0.0002438059,0.00002046514,0.0165088,0.02651195,0.216798,0.5339902,0.0004474328,0.001294652],"study_design_scores_gemma":[0.002189697,0.0007415,0.6175831,0.00003064378,0.0001641089,0.000278428,0.000698861,0.09299911,0.02355004,0.261087,0.0003886276,0.0002888779],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939894,0.00004561663,0.002459744,0.001346497,0.0002235429,0.0004095779,0.00003481337,0.00002888661,0.001461904],"genre_scores_gemma":[0.9981992,0.000002689892,0.0001512901,0.001457865,0.0001357111,0.00001653791,0.00002270165,0.000005953845,0.000008062584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4146777,"threshold_uncertainty_score":0.2417222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04881452641210886,"score_gpt":0.3199650258218852,"score_spread":0.2711504994097763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}