{"id":"W2901104279","doi":"10.1101/478198","title":"Gene knock out of honey bee trypanosomatid parasite, <i>Lotmaria passim</i> , by CRISPR/Cas9 system","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Xi’an Jiaotong-Liverpool University; McGill University; Harvard T.H. Chan School of Public Health","keywords":"Biology; CRISPR; Honey bee; Gene; Genetics; Plasmid; Cas9; Electroporation; Ecology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001674543,0.0003727537,0.0002833029,0.0002850808,0.0002305786,0.0003507145,0.0003667234,0.0004169843,0.001826423],"category_scores_gemma":[0.0001286003,0.0001963513,0.0003005934,0.0001146649,0.0002693518,0.0001789524,0.0004807044,0.0005640311,0.0009145065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003090632,"about_ca_system_score_gemma":0.0001957394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009504121,"about_ca_topic_score_gemma":0.0015903,"domain_scores_codex":[0.9998585,0.00001492477,0.0000194894,0.000046855,0.00003852797,0.00002163942],"domain_scores_gemma":[0.9998646,0.00002028871,0.00005932798,0.00002368006,0.00001158484,0.00002055798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001348865,0.000006952645,0.0001125916,0.00002552967,0.000003262597,0.00004811354,0.00001933878,0.00002845494,0.9989583,0.0001259403,0.00006839617,0.0005896206],"study_design_scores_gemma":[0.000007736924,0.00006221855,0.002272663,0.000008507183,0.00001370344,0.0002768841,0.00002543691,0.001021561,0.9899374,0.00002724216,0.006339727,0.00000683142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711484,0.0005847219,0.01975016,0.0002474485,0.00007651559,0.0001745546,0.001858731,0.001110908,0.005048438],"genre_scores_gemma":[0.9715226,0.0003423995,0.01527924,0.0001129384,0.00001278906,0.0001379824,0.002163171,0.000215243,0.01021371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001826423,"threshold_uncertainty_score":0.006110013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0209444512226857,"score_gpt":0.2346960202399085,"score_spread":0.2137515690172228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}