{"id":"W2901147189","doi":"10.1194/jlr.m088070","title":"Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2 mice","year":2018,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Centre for Applied Research in Cancer Control; Jewish General Hospital; University of Victoria; McGill University; University of British Columbia; BC Cancer Agency; Simon Fraser University","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute","keywords":"Phospholipid; Chemistry; Liver damage; Bile acid; Biochemistry; Internal medicine; Gastroenterology; Medicine; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003345141,0.0001579954,0.00056748,0.000625441,0.00007465577,0.00001560051,0.0003794527,0.000170682,0.0008035089],"category_scores_gemma":[0.0001853489,0.0001129791,0.0002000388,0.0008752682,0.0004373236,0.0001551933,0.00006307916,0.0009854656,0.00004992678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000168534,"about_ca_system_score_gemma":0.0005018684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006778764,"about_ca_topic_score_gemma":0.00007112304,"domain_scores_codex":[0.9967591,0.0002497356,0.0008264395,0.0002317434,0.001407644,0.0005253172],"domain_scores_gemma":[0.9981045,0.0001582359,0.0002345193,0.0003626834,0.0008311105,0.0003090035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002198352,0.00227359,0.01498504,0.0006357214,0.0001622235,0.000602681,0.002194318,0.00000705775,0.9488251,0.00005001028,0.02588076,0.002185124],"study_design_scores_gemma":[0.00531646,0.004045464,0.03350289,0.001637369,0.00008300362,0.0001065884,0.0007614504,0.0002169864,0.9047822,0.0002946997,0.04902345,0.0002293907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945148,0.001356101,0.00005144658,0.001433228,0.0003737918,0.0003722821,0.00001444643,0.000007516979,0.001876394],"genre_scores_gemma":[0.9921604,0.001404352,0.0003855843,0.00009257762,0.0009338065,0.000005210379,0.000005120497,0.00003473794,0.004978241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04404287,"threshold_uncertainty_score":0.8797859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07300001877966018,"score_gpt":0.378988887263709,"score_spread":0.3059888684840488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}