{"id":"W2901150882","doi":"10.1159/000494331","title":"Variants in <b><i>APOA5</i></b> and <b><i>ADIPOQ</i></b> Moderate Improvements in Metabolic Syndrome during a One-Year Lifestyle Intervention","year":2018,"lang":"en","type":"article","venue":"Lifestyle Genomics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Alberta; St. Michael's Hospital; University of Guelph","funders":"Hospital for Sick Children","keywords":"Single-nucleotide polymorphism; Adiponectin; Medicine; Minor allele frequency; Metabolic syndrome; Dyslipidemia; Internal medicine; Cohort; Obesity; Genetics; Biology; Insulin resistance; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006209775,0.0004845118,0.0002987381,0.0002733096,0.000349288,0.0003082813,0.0004586192,0.0002964267,0.00213306],"category_scores_gemma":[0.0008551833,0.0001297926,0.0005932124,0.0006319818,0.0003718206,0.0001037295,0.0002215148,0.0003988512,0.0002077058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007928719,"about_ca_system_score_gemma":0.0009627742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08102149,"about_ca_topic_score_gemma":0.1530295,"domain_scores_codex":[0.9996237,0.00006307216,0.00003752229,0.000134453,0.00009060642,0.00005073416],"domain_scores_gemma":[0.999535,0.0001029992,0.0001923657,0.00004110095,0.00004323429,0.00008540379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003847243,0.0003730594,0.9764058,0.00008704305,0.0007906759,0.0002356705,0.0002094263,0.0003072691,0.009561264,0.0001096024,0.0003563786,0.007716487],"study_design_scores_gemma":[0.00009082854,0.0003574411,0.9982074,0.00001004109,0.0002061363,0.00009168673,0.00003475886,0.00017241,0.0004624855,0.00003162441,0.0003311779,0.000003982842],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973911,0.0002361262,0.0003914018,0.0000521991,0.000009567426,0.00006542671,0.001154494,0.000009188399,0.0006903838],"genre_scores_gemma":[0.9978548,0.00008570984,0.0006417164,0.00005181128,0.000007208037,0.00005082515,0.0007980792,0.000005089439,0.0005047596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08102149,"threshold_uncertainty_score":0.1610998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048040013466687,"score_gpt":0.2390906947410221,"score_spread":0.2286102946063552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}