{"id":"W2901150882","doi":"10.1159/000494331","title":"Variants in <b><i>APOA5</i></b> and <b><i>ADIPOQ</i></b> Moderate Improvements in Metabolic Syndrome during a One-Year Lifestyle Intervention","year":2018,"lang":"en","type":"article","venue":"Lifestyle Genomics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; University of Alberta; St. Michael's Hospital; University of Guelph","funders":"Hospital for Sick Children","keywords":"Single-nucleotide polymorphism; Adiponectin; Medicine; Minor allele frequency; Metabolic syndrome; Dyslipidemia; Internal medicine; Cohort; Obesity; Genetics; Biology; Insulin resistance; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.004192486,0.002118406,0.002965812,0.001207789,0.001054786,0.0004649176,0.001964021,0.002430134,0.000284851],"category_scores_gemma":[0.001364167,0.002437503,0.000943938,0.001267137,0.0008141752,0.0002262601,0.00215003,0.001045158,0.0004793405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008417038,"about_ca_system_score_gemma":0.0008247155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001487108,"about_ca_topic_score_gemma":0.00568604,"domain_scores_codex":[0.985833,0.001669986,0.00400479,0.003749778,0.001027656,0.003714762],"domain_scores_gemma":[0.9928591,0.0003113299,0.002097464,0.002806657,0.0007442321,0.001181248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007228854,0.001500387,0.007792603,0.0003319427,0.001408727,0.0001444026,0.001006747,0.00135295,0.9775084,0.002746894,0.00294028,0.002543816],"study_design_scores_gemma":[0.02686891,0.005008492,0.5776527,0.001139467,0.002013433,0.0008745487,0.0002614566,0.02054586,0.04936917,0.004641863,0.3031311,0.008493011],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773316,0.0118947,0.001940827,0.0007239601,0.002053002,0.002438355,0.0008966534,0.0001982453,0.002522615],"genre_scores_gemma":[0.9750363,0.008673465,0.005741012,0.0008546326,0.001868672,0.0006270517,0.00138813,0.0005014669,0.005309286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9281392,"threshold_uncertainty_score":0.9991557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048040013466687,"score_gpt":0.2390906947410221,"score_spread":0.2286102946063552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}