{"id":"W2901182872","doi":"10.1093/annonc/mdy436.027","title":"GOG 3016/ENGOT-cx9: An open-label, multi-national, randomized, phase III trial of cemiplimab, an anti-PD-1, versus investigator's choice (IC) chemotherapy in ≥ second-line recurrent or metastatic cervical cancer","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Cycle for Survival","keywords":"Medicine; Chemotherapy; Bevacizumab; Vinorelbine; Internal medicine; Gemcitabine; Irinotecan; Oncology; Surgery; Cancer; Cisplatin; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001434412,0.001430461,0.002086374,0.0005197453,0.0004984114,0.001035675,0.001110219,0.001799289,0.01114221],"category_scores_gemma":[0.001094567,0.0004916569,0.001253574,0.0004401875,0.001077765,0.001242537,0.0004292099,0.004381621,0.001567836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009701872,"about_ca_system_score_gemma":0.001547527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00150991,"about_ca_topic_score_gemma":0.006244267,"domain_scores_codex":[0.999634,0.0001742834,0.000013474,0.00007056602,0.00002704034,0.00008062037],"domain_scores_gemma":[0.9994798,0.0001192151,0.00008517045,0.00003349722,0.00002334596,0.0002589577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9037457,0.01799753,0.0009254221,0.001024263,0.0007651129,0.00006217035,0.0001015849,0.00107961,0.00609777,0.000581646,0.004966421,0.0626528],"study_design_scores_gemma":[0.9300885,0.06550899,0.00122468,0.0000392784,0.0002283811,0.0000497697,0.00003380257,0.0005931444,0.0004693262,0.000271699,0.001476727,0.00001572215],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.969452,0.005189703,0.001367663,0.002345438,0.0009418342,0.007215235,0.004642817,0.0006085919,0.008236749],"genre_scores_gemma":[0.9698807,0.003136675,0.003639837,0.002918927,0.00036913,0.006609121,0.003856474,0.00008724717,0.009501847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01114221,"threshold_uncertainty_score":0.03727448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3848825328179828,"score_gpt":0.5344764449217434,"score_spread":0.1495939121037606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}