{"id":"W2901206051","doi":"10.1242/jcs.225144","title":"Direct binding of Talin to Rap1 is required for cell–ECM adhesion in <i>Drosophila</i>","year":2018,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Human Frontier Science Program","keywords":"Biology; Rap1; Cell biology; Cell adhesion; Drosophila (subgenus); Adhesion; Focal adhesion; Cell; Genetics; Signal transduction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007225206,0.00006837108,0.0001247404,0.0001604197,0.0000765018,0.00002218605,0.0003073168,0.00004563337,0.00002050071],"category_scores_gemma":[0.0001128794,0.00005874829,0.00009444061,0.0002992624,0.00007254642,0.000015965,0.00007593731,0.00004935011,0.000004138016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002508759,"about_ca_system_score_gemma":0.0001476211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005934357,"about_ca_topic_score_gemma":0.000005835944,"domain_scores_codex":[0.99914,0.00001464428,0.0003073993,0.0001671374,0.0001950655,0.0001758137],"domain_scores_gemma":[0.9991929,0.00001428019,0.0002467888,0.0001583982,0.0002918615,0.00009579395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007105715,0.0000657205,0.00006230232,0.000007850613,0.000001835283,9.125566e-7,0.0001052248,0.000006910694,0.9978501,0.00001082261,0.001599343,0.0002178745],"study_design_scores_gemma":[0.0003056748,0.001090145,0.00004701835,0.00003482325,0.000005853296,0.000006086672,0.00006950875,0.0001584198,0.9810888,0.00005755325,0.01706788,0.00006828672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951196,0.0001257228,0.001797943,0.0001743693,0.0004388837,0.00009993542,0.000007758616,8.638623e-7,0.002234933],"genre_scores_gemma":[0.9964008,0.00008642265,0.002641752,0.0001623336,0.0001847825,0.000001583213,0.000001107544,0.00000670434,0.0005145354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01676139,"threshold_uncertainty_score":0.2395686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621027987521003,"score_gpt":0.2845683628960266,"score_spread":0.2683580830208166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}