{"id":"W2901208726","doi":"10.1016/j.cmet.2018.10.007","title":"Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis","year":2018,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Eye Institute; Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center; Crohn's and Colitis Canada; Human Islet Research Network; Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center; Juvenile Diabetes Research Foundation United States of America; National Institutes of Health; Vanderbilt-Ingram Cancer Center; Canadian Institutes of Health Research; Leona M. and Harry B. Helmsley Charitable Trust; U.S. Department of Veterans Affairs","keywords":"In vivo; Biology; Antibody; Cell sorting; Cell biology; Cell; Pancreas; In vitro; Cell type; Molecular biology; Immunology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003180969,0.0005727193,0.0002325979,0.0004311171,0.0003300763,0.0006242858,0.0003869824,0.000503402,0.003280294],"category_scores_gemma":[0.0001483608,0.0003297256,0.0003220227,0.0003286833,0.0002104767,0.000353953,0.0002578444,0.001395518,0.001341889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003481914,"about_ca_system_score_gemma":0.0002900809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006107306,"about_ca_topic_score_gemma":0.001301549,"domain_scores_codex":[0.9998096,0.00003019498,0.000018232,0.00004741195,0.00004620627,0.00004841041],"domain_scores_gemma":[0.9998752,0.0000379698,0.00002109371,0.00002042381,0.00001626353,0.00002903803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008487485,0.00003406174,0.0001400975,0.00002217165,0.000006202205,0.00007801659,0.00001297106,0.00004266192,0.9980057,0.0003258588,0.00007559537,0.001171899],"study_design_scores_gemma":[0.00001821511,0.0000850311,0.001252349,0.000004651459,0.00001472298,0.0003161612,0.00001910697,0.0006193168,0.9936841,0.00009084973,0.003893826,0.000001659871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8765101,0.004276278,0.09812642,0.0006994458,0.000281941,0.0002829616,0.002237814,0.0007502909,0.01683475],"genre_scores_gemma":[0.9069533,0.004493864,0.0652359,0.0002970349,0.00007037371,0.0003952107,0.004088668,0.0003205716,0.01814509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003280294,"threshold_uncertainty_score":0.01097363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005147126249620205,"score_gpt":0.247420458991037,"score_spread":0.2422733327414168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}