{"id":"W2901208726","doi":"10.1016/j.cmet.2018.10.007","title":"Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis","year":2018,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Eye Institute; Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center; Crohn's and Colitis Canada; Human Islet Research Network; Vanderbilt Digestive Diseases Research Center, Vanderbilt University Medical Center; Juvenile Diabetes Research Foundation United States of America; National Institutes of Health; Vanderbilt-Ingram Cancer Center; Canadian Institutes of Health Research; Leona M. and Harry B. Helmsley Charitable Trust; U.S. Department of Veterans Affairs","keywords":"In vivo; Biology; Antibody; Cell sorting; Cell biology; Cell; Pancreas; In vitro; Cell type; Molecular biology; Immunology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002295655,0.000227309,0.0004376995,0.0002181595,0.00008596859,0.00003100558,0.0001628532,0.0001560566,0.00004652818],"category_scores_gemma":[0.00003622403,0.0002196764,0.0001452771,0.0004160375,0.0000853252,0.000008539358,0.0000740755,0.0000843618,0.000003336421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008451812,"about_ca_system_score_gemma":0.00002508522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004090412,"about_ca_topic_score_gemma":0.00009814627,"domain_scores_codex":[0.998593,0.0000617809,0.0003612674,0.0005020669,0.0000934661,0.0003884682],"domain_scores_gemma":[0.9993836,0.00002664013,0.0001147017,0.0002982026,0.00008260681,0.00009421042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002157158,0.00008428751,0.002640412,0.00002559432,0.00009408107,0.000006387531,0.000108098,0.0001078709,0.9961869,0.00001519731,0.0004324268,0.00008309077],"study_design_scores_gemma":[0.001663611,0.00007466979,0.003328152,0.000008798761,0.0002828168,9.795081e-7,0.00003409784,0.001113812,0.9873887,0.00009018106,0.005748029,0.0002661007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898988,0.008575081,0.0006718776,0.00002539829,0.0001125929,0.0002914059,0.00004582985,0.000009448137,0.0003695895],"genre_scores_gemma":[0.9968901,0.0003667949,0.001290287,0.0002435398,0.0002881193,0.00004170159,0.0001201583,0.00003131403,0.0007280135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008798086,"threshold_uncertainty_score":0.8958142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005147126249620205,"score_gpt":0.247420458991037,"score_spread":0.2422733327414168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}