{"id":"W2901300423","doi":"10.1016/j.bbabio.2018.09.285","title":"Calcineurin-homologous proteins bind with high affinity to the CBD-region of the human Na+/H+ exchanger NHE1","year":2018,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Bioenergetics","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Calcineurin; Chemistry; Sodium–hydrogen antiporter; Homologous chromosome; Cell biology; Biochemistry; Biophysics; Biology; Sodium; Medicine; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000304778,0.0004564083,0.0005749176,0.0005074863,0.0006823991,0.00065123,0.0006368057,0.0005401063,0.004692598],"category_scores_gemma":[0.0006017041,0.0002695508,0.0004890966,0.0004060483,0.0003511207,0.0002340869,0.0005715077,0.0007389266,0.001515845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000253,"about_ca_system_score_gemma":0.0004366325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004651784,"about_ca_topic_score_gemma":0.006474909,"domain_scores_codex":[0.9996547,0.00003982343,0.00001471462,0.0001046618,0.00009891394,0.00008732172],"domain_scores_gemma":[0.9995999,0.0001248546,0.00005897992,0.00004735095,0.00005980346,0.0001091702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002217719,0.00006236356,0.001273443,0.0001489413,0.00002870649,0.00007583224,0.00006156129,0.00006079512,0.9950979,0.0001674597,0.0003197324,0.002481425],"study_design_scores_gemma":[0.0001930345,0.0003400163,0.09191269,0.00006559711,0.00006626447,0.001950626,0.0001746039,0.002640964,0.8828573,0.000354132,0.01939864,0.00004611734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9692667,0.01717552,0.004864626,0.0006863104,0.0001625485,0.00008977511,0.0006757369,0.0002019871,0.00687665],"genre_scores_gemma":[0.9805937,0.003252583,0.004233726,0.0003853874,0.0001135275,0.00004430263,0.00286209,0.0000526902,0.008461976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004692598,"threshold_uncertainty_score":0.01569825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02150145105172352,"score_gpt":0.2567849900946536,"score_spread":0.2352835390429301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}