{"id":"W2901308104","doi":"10.1007/s11060-018-03038-2","title":"International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma","year":2018,"lang":"en","type":"article","venue":"Journal of Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Institute for Health and Care Research; Cure Brain Cancer Foundation; Medical Research Council; Children’s Hospital of Wisconsin Research Institute; CHILDREN with CANCER UK; Brain Tumour Charity; Murdoch Children's Research Institute; National Health and Medical Research Council; Cancer Research UK; Royal Children's Hospital Foundation; Children's Hospital Foundation; Brain Research UK; Cure Starts Now Foundation","keywords":"Glioma; In vitro; In vivo; Biopsy; Medicine; Pathology; Cancer research; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01010183,0.000859599,0.0005390063,0.0004338695,0.0004241499,0.001370384,0.001034332,0.0008347375,0.002305136],"category_scores_gemma":[0.002287732,0.0001678589,0.0006552937,0.0006407932,0.0007504181,0.001228073,0.001072784,0.001861306,0.001038667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00043487,"about_ca_system_score_gemma":0.0006373434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005950048,"about_ca_topic_score_gemma":0.0009405965,"domain_scores_codex":[0.9978979,0.001155486,0.0001647494,0.0002251905,0.0003322765,0.0002244289],"domain_scores_gemma":[0.9984438,0.0004625072,0.0001280651,0.0003738004,0.0003198891,0.0002718836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004703811,0.007301316,0.0185198,0.001203951,0.0005811033,0.004027231,0.003666499,0.006397689,0.7114679,0.01015655,0.009540659,0.2224333],"study_design_scores_gemma":[0.0007996073,0.03287749,0.02444986,0.000432752,0.001141931,0.02314427,0.001759393,0.004256593,0.7500962,0.002646866,0.1582724,0.0001226191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8737317,0.03318263,0.05217264,0.002161295,0.0005382953,0.000670811,0.001084942,0.0003448914,0.03611275],"genre_scores_gemma":[0.9326668,0.03212998,0.02368912,0.000728666,0.0001710348,0.0003081564,0.003735733,0.0002017546,0.006368774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01010183,"threshold_uncertainty_score":0.0534243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0420929085945313,"score_gpt":0.3257757592576024,"score_spread":0.2836828506630711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}