{"id":"W2901308104","doi":"10.1007/s11060-018-03038-2","title":"International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma","year":2018,"lang":"en","type":"article","venue":"Journal of Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Institute for Health and Care Research; Cure Brain Cancer Foundation; Medical Research Council; Children’s Hospital of Wisconsin Research Institute; CHILDREN with CANCER UK; Brain Tumour Charity; Murdoch Children's Research Institute; National Health and Medical Research Council; Cancer Research UK; Royal Children's Hospital Foundation; Children's Hospital Foundation; Brain Research UK; Cure Starts Now Foundation","keywords":"Glioma; In vitro; In vivo; Biopsy; Medicine; Pathology; Cancer research; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197098,0.0001035462,0.0003889363,0.0003323209,0.00002580302,0.000005062358,0.0002111382,0.00005761158,0.00004575006],"category_scores_gemma":[0.0001834455,0.00006373059,0.00009638113,0.0002195919,0.0001472334,0.00009343839,0.0000715978,0.0001443877,0.000001454558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001073837,"about_ca_system_score_gemma":0.0002018261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006490288,"about_ca_topic_score_gemma":0.00002082509,"domain_scores_codex":[0.998422,0.00009971125,0.0008598226,0.0001071158,0.0003694419,0.0001418718],"domain_scores_gemma":[0.9985011,0.0002235785,0.0006841532,0.0001422676,0.0003829221,0.00006595321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001465209,0.005751621,0.0212281,0.00001948207,0.0002065988,0.001024364,0.03890194,0.00002741669,0.8653654,0.0001290736,0.0004260266,0.06545477],"study_design_scores_gemma":[0.01669689,0.01359107,0.1273298,0.000277187,0.0001773992,0.002884302,0.007157087,0.0003644086,0.7985002,0.0002770045,0.03255912,0.0001855114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996911,0.00009280992,0.00006988172,0.001834021,0.0003923313,0.0001682661,0.000001678876,0.000002382515,0.000527588],"genre_scores_gemma":[0.9964312,0.00005364427,0.003093962,0.0003106329,0.0000891813,0.00001157174,0.000001301828,0.000007707349,7.927414e-7],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1061017,"threshold_uncertainty_score":0.2598858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0420929085945313,"score_gpt":0.3257757592576024,"score_spread":0.2836828506630711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}