{"id":"W2901441194","doi":"10.1021/acs.bioconjchem.8b00787","title":"Surfactant-Free Direct Access to Porphyrin-Cross-Linked Nanogels for Photodynamic and Photothermal Therapy","year":2018,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Boğaziçi Üniversitesi; Public Health Agency of Canada","keywords":"Porphyrin; Chemistry; Photodynamic therapy; Singlet oxygen; Photothermal therapy; Photochemistry; Linker; Pulmonary surfactant; Irradiation; Combinatorial chemistry; Nanotechnology; Organic chemistry; Oxygen; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001231201,0.0003487313,0.0003062821,0.00003700445,0.0001217063,0.0002088827,0.0006135777,0.0001995749,0.0002335837],"category_scores_gemma":[0.00004208703,0.0003380365,0.00008353347,0.0001745742,0.000151034,0.0002181197,0.0001122961,0.0001086622,0.00001855136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001107249,"about_ca_system_score_gemma":0.00004135981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002160856,"about_ca_topic_score_gemma":0.00001117137,"domain_scores_codex":[0.9986445,0.000003352555,0.0002988641,0.0003894139,0.0001511121,0.0005127321],"domain_scores_gemma":[0.9989628,0.00006165552,0.00005549163,0.0006102459,0.0001088838,0.0002009292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000212608,0.0000161206,0.0004173519,0.0001618916,0.0001057925,0.000002924699,0.0001036555,0.00004467638,0.9963704,0.000002118566,0.0008937658,0.001668636],"study_design_scores_gemma":[0.001730768,0.00006976592,0.0008381475,0.00004859994,0.0000144109,0.000008404339,0.00000887873,0.0009071007,0.9764872,0.0001898371,0.01924161,0.000455315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938331,0.0005826139,0.0003532582,0.00003111979,0.0004258465,0.0007354327,0.0005933246,0.0003873776,0.003057965],"genre_scores_gemma":[0.9978493,0.0002081113,0.0005253547,0.0001929825,0.0003878849,0.0001647151,0.00004517245,0.0001357721,0.0004907065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0198833,"threshold_uncertainty_score":0.9999072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01744205010446506,"score_gpt":0.2700180348056629,"score_spread":0.2525759847011979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}