{"id":"W2901484586","doi":"10.1002/jlb.1ru0818-310r","title":"Macrophage immunomodulation in chronic osteolytic diseases—the case of periodontitis","year":2018,"lang":"en","type":"review","venue":"Journal of Leukocyte Biology","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; U.S. Public Health Service; National Institutes of Health","keywords":"Inflammation; Immunology; Periodontitis; Biology; Proinflammatory cytokine; Context (archaeology); Immune system; Macrophage; Innate immune system; Acquired immune system; Myeloid; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004357215,0.0005305697,0.0009305311,0.002066557,0.0003424615,0.001015607,0.0004931662,0.001251653,0.002496231],"category_scores_gemma":[0.0007440204,0.0002187108,0.0004308449,0.001425773,0.0005074024,0.001172511,0.0006378405,0.00157453,0.001297507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022838,"about_ca_system_score_gemma":0.0008580519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008605924,"about_ca_topic_score_gemma":0.001643097,"domain_scores_codex":[0.999799,0.0000382274,0.00003765025,0.00003099374,0.00007565129,0.00001852941],"domain_scores_gemma":[0.999733,0.0001269183,0.00003637634,0.000008968571,0.00007077413,0.00002387895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009366243,0.00006199785,0.0002850995,0.01793438,0.00008513589,0.0005432661,0.0001859099,0.0001836842,0.002154701,0.005510596,0.03944656,0.933515],"study_design_scores_gemma":[0.00001080652,0.0000719177,0.0009291381,0.004310898,0.00007702829,0.00323097,0.000121415,0.0000499732,0.0003766415,0.002318971,0.9884859,0.00001627199],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001118869,0.9986691,0.0000604794,0.000320252,0.0002299168,0.000002618808,0.000007556901,0.000003249922,0.0005950015],"genre_scores_gemma":[0.0009893096,0.9977897,0.0001584138,0.0002669177,0.0003027945,0.000004942882,0.00001356598,0.000001098374,0.0004731606],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002496231,"threshold_uncertainty_score":0.00835079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04263321713940404,"score_gpt":0.3881516506922017,"score_spread":0.3455184335527977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}