{"id":"W2901557802","doi":"10.1038/s41586-018-0702-1","title":"Protocadherin-1 is essential for cell entry by New World hantaviruses","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institute for Advanced Research; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Agence Nationale de la Recherche","keywords":"Hantavirus; Hantavirus pulmonary syndrome; Virology; Biology; Hantavirus Infection; Virus; Immunology; Protocadherin; Genetics; Cell; Cadherin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000352135,0.0001048516,0.0001293018,0.00005817729,0.00008479659,0.00002186682,0.00005185915,0.0004146321,0.001198533],"category_scores_gemma":[0.00001884213,0.00008178688,0.00008932591,0.0001900607,0.00003763348,0.00005227798,0.00001671629,0.0006180007,0.0001163989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002529216,"about_ca_system_score_gemma":0.00006881261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006278302,"about_ca_topic_score_gemma":0.00005950492,"domain_scores_codex":[0.9994195,0.000005858427,0.000101455,0.0001851504,0.0001102451,0.00017779],"domain_scores_gemma":[0.9996118,0.00001307446,0.00003732248,0.0001609292,0.00007485672,0.0001020384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001939602,0.0001171382,0.002702834,0.00005258383,0.00002398569,0.00000139137,0.00007504029,2.824753e-8,0.05844779,0.00008269084,0.9367307,0.001571835],"study_design_scores_gemma":[0.0008104122,0.0002983382,0.0002765127,0.00002629024,0.00003542611,0.000003800366,0.00000830736,0.00001446878,0.3741009,0.00005735576,0.6243043,0.00006390779],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8788946,0.004229154,0.003587533,0.01190286,0.00526942,0.01088331,0.0002559332,0.0005817706,0.08439538],"genre_scores_gemma":[0.8531012,0.00001947807,0.001030311,0.005834802,0.002739091,0.0001033729,0.00003231645,0.00003225467,0.1371072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3156531,"threshold_uncertainty_score":0.9997145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01183608789791701,"score_gpt":0.3246617082476921,"score_spread":0.3128256203497751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}