{"id":"W2901658913","doi":"10.1161/circ.132.suppl_3.17586","title":"Abstract 17586: HSP27 Mediated Atheroprotection Requires GM-CSF Induction: Potential Role in Reverse Cholesterol Transport? <i>(Best of Basic Science Abstract)</i>","year":2015,"lang":"en","type":"article","venue":"Circulation","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Hsp27; ABCA1; Medicine; Reverse cholesterol transport; Apolipoprotein B; Cholesterol; ABCG1; Endocrinology; Internal medicine; Molecular biology; Heat shock protein; Biology; Hsp70; Transporter; Biochemistry; Lipoprotein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003177005,0.00110102,0.0006595989,0.0003599531,0.0002883254,0.0005494051,0.0006501024,0.0007017539,0.01390361],"category_scores_gemma":[0.0001672415,0.0002249348,0.0005422162,0.0003343271,0.0006870358,0.000325478,0.0003156469,0.00101915,0.005730184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005162263,"about_ca_system_score_gemma":0.0003529169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006989847,"about_ca_topic_score_gemma":0.0003947816,"domain_scores_codex":[0.9998685,0.00001510437,0.00001461334,0.00003272549,0.00003847861,0.0000305088],"domain_scores_gemma":[0.9998845,0.0000222338,0.00002761542,0.00001304163,0.00002362306,0.00002891563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003354736,0.0003591748,0.0005524405,0.001817899,0.00008002306,0.0009582371,0.00005879454,0.0001970191,0.9538494,0.001723228,0.01077969,0.02626937],"study_design_scores_gemma":[0.0004764204,0.002795472,0.02467518,0.0003030488,0.0002137564,0.003368483,0.0001145632,0.001179086,0.8508567,0.00102959,0.1149528,0.00003491132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6837768,0.1550228,0.0197307,0.02538849,0.007099643,0.00106573,0.01858993,0.002164697,0.08716124],"genre_scores_gemma":[0.7732648,0.06326203,0.01059442,0.004419425,0.005924233,0.0007389701,0.02463414,0.00030018,0.1168618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01390361,"threshold_uncertainty_score":0.04651225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02965762603360143,"score_gpt":0.2861731560674483,"score_spread":0.2565155300338469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}