{"id":"W2901744769","doi":"10.3389/fimmu.2018.02494","title":"Natural Killer Cells Adapt to Cytomegalovirus Along a Functionally Static Phenotypic Spectrum in Human Immunodeficiency Virus Infection","year":2018,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Memorial University of Newfoundland; Beatrice Hunter Cancer Research Institute; Cancer Research Institute","keywords":"Antibody-dependent cell-mediated cytotoxicity; Human cytomegalovirus; CD16; Natural killer cell; Biology; Degranulation; Immunology; Cytotoxicity; Interferon; Fc receptor; Lymphokine-activated killer cell; Interleukin 12; Perforin; Virology; Antibody; Interleukin 21; Virus; Receptor; Immune system; Cytotoxic T cell; In vitro; T cell; Monoclonal antibody; CD8; CD3","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001374344,0.0001631246,0.0001750352,0.0001266683,0.0001038823,0.0002255083,0.00009612102,0.0001519596,0.0004607631],"category_scores_gemma":[0.0002167021,0.0001059953,0.0001181542,0.00009793845,0.0001919659,0.0001651569,0.000216261,0.0002433973,0.00009186564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009846829,"about_ca_system_score_gemma":0.00005814719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000191704,"about_ca_topic_score_gemma":0.0002809841,"domain_scores_codex":[0.9999002,0.00002199176,0.000008183418,0.00002145611,0.00001921533,0.00002893051],"domain_scores_gemma":[0.9999247,0.00001489487,0.00001427046,0.00001506577,0.0000112474,0.00001991579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004172369,0.00003470748,0.01579089,0.00002064393,0.00000711508,0.000208433,0.0001038788,0.00009795611,0.9809954,0.00003491021,0.00001064252,0.002278185],"study_design_scores_gemma":[0.00003302532,0.003138279,0.6646432,0.00001697224,0.00005512697,0.003956325,0.0005712645,0.001035621,0.3250996,0.0002236209,0.001207837,0.00001917969],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996431,0.0001314384,0.00009534939,0.000003222572,0.000001210058,0.000004300754,0.00001552923,0.000001637143,0.0001042395],"genre_scores_gemma":[0.9995112,0.0001017167,0.000130285,0.000009956042,0.000002743872,0.000007315937,0.00006651261,0.000001121873,0.000169096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004607631,"threshold_uncertainty_score":0.001541436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007467566988018366,"score_gpt":0.2276115600443063,"score_spread":0.220143993056288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}