{"id":"W2901765588","doi":"10.1002/pep2.24082","title":"Synthesis of 3a‐hydroxyhexahydropyrrolo[2,3‐B]Indole‐2‐carboxamide, an oxidation product of tryptophan present in natural products","year":2018,"lang":"en","type":"article","venue":"Peptide Science","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indole test; Tryptophan; Chemistry; Dimethyldioxirane; Natural product; Carboxamide; Stereochemistry; Organic chemistry; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001376044,0.0002047416,0.0004149802,0.0005918615,0.0001072487,0.00003407561,0.001033729,0.00006002752,0.00009640549],"category_scores_gemma":[0.00317247,0.000178739,0.00007556719,0.003095608,0.001291061,0.0006655443,0.0001825862,0.0001360126,0.00001302982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001103045,"about_ca_system_score_gemma":0.0002428252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004468758,"about_ca_topic_score_gemma":0.00005224198,"domain_scores_codex":[0.9970428,0.0000516869,0.0006092808,0.0008461423,0.0009952368,0.0004548505],"domain_scores_gemma":[0.9977835,0.0001587944,0.0004338568,0.001037423,0.0004856829,0.0001007133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003914455,0.0002356698,0.005820028,0.0001136627,0.00001389851,0.000001302011,0.0004355107,0.00002074424,0.9563766,0.0000664809,0.00002692511,0.03685002],"study_design_scores_gemma":[0.0001328624,0.00004302395,0.02312738,0.00009228027,0.00002662789,0.000004494408,0.0002736819,0.002089143,0.9738657,0.00007192256,0.00008479772,0.0001880184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872409,0.0002176045,0.000009250169,0.0001330451,0.0001199424,0.0001340094,0.000008629619,0.00003242067,0.01210424],"genre_scores_gemma":[0.9982116,0.00001936271,0.001107985,0.000006997322,0.0002747825,0.00002803001,0.000005063089,0.0000169295,0.0003292246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.036662,"threshold_uncertainty_score":0.7288766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238892816726355,"score_gpt":0.2558187202976485,"score_spread":0.2434297921303849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}