{"id":"W2901822462","doi":"10.1016/j.clinthera.2018.10.014","title":"Effects of a Self–micro-emulsifying Delivery System Formulation Versus a Standard ω-3 Acid Ethyl Ester Product on the Bioavailability of Eicosapentaenoic Acid and Docosahexaenoic Acid: A Study in Healthy Men and Women in a Fasted State","year":2018,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"AstraZeneca Schweiz; Diagnostic Services Manitoba; Regeneron Pharmaceuticals; Amgen Foundation; Alere; Amarin Corporation; Pharmavite; Amgen","keywords":"Bioavailability; Eicosapentaenoic acid; Docosahexaenoic acid; Medicine; Crossover study; Ingestion; Capsule; Dosing; Bioequivalence; Fatty acid; Pharmacology; Internal medicine; Chemistry; Biochemistry; Polyunsaturated fatty acid; Placebo; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001122262,0.000619699,0.000944515,0.0002619025,0.0004256967,0.0004230015,0.0003225875,0.0008024207,0.002713362],"category_scores_gemma":[0.0009939702,0.0005946587,0.0008510043,0.0002020768,0.0007013197,0.0005147915,0.000320305,0.0009988358,0.0002966775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003229737,"about_ca_system_score_gemma":0.0003952913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007655581,"about_ca_topic_score_gemma":0.001360101,"domain_scores_codex":[0.9994,0.0002292646,0.00005740105,0.0001479507,0.00008400963,0.00008135282],"domain_scores_gemma":[0.9992756,0.0002027523,0.0001911379,0.00006111279,0.00006117601,0.0002081354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7821541,0.06620687,0.005365837,0.0004807584,0.0006384403,0.0001064113,0.0002907547,0.0002213139,0.1126085,0.00008150398,0.0002166672,0.0316289],"study_design_scores_gemma":[0.03760686,0.9201081,0.02655393,0.00001436651,0.000495076,0.00005885182,0.0001296072,0.0005083613,0.0138392,0.00004545457,0.0006120306,0.00002810504],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992082,0.0003098171,0.0001042836,0.00002468752,0.00003220877,0.0001574091,0.00004728714,0.000005722473,0.0001105949],"genre_scores_gemma":[0.996628,0.0005234936,0.001041171,0.0001358569,0.00008334191,0.0003030471,0.0001350101,0.000006261007,0.00114391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002713362,"threshold_uncertainty_score":0.009077072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07939323623796085,"score_gpt":0.3966575434453349,"score_spread":0.317264307207374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}