{"id":"W2901827169","doi":"10.1002/tox.22681","title":"Para‐tertiary butyl catechol (PTBC), an industrial antioxidant induces human platelet apoptosis","year":2018,"lang":"en","type":"article","venue":"Environmental Toxicology","topic":"Contact Dermatitis and Allergies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Manitoba","funders":"","keywords":"Reactive oxygen species; Chemistry; Apoptosis; Platelet; Platelet activation; Mitochondrial permeability transition pore; Antioxidant; Phosphatidylserine; Glutathione; Pharmacology; Biochemistry; Cell biology; Immunology; Programmed cell death; Biology; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009829267,0.0001711658,0.0001163135,0.0001073893,0.0000958192,0.0001340559,0.00006525752,0.0001939408,0.00101437],"category_scores_gemma":[0.0001292444,0.00007104291,0.0001738572,0.0001100355,0.00008295154,0.0001086905,0.0001041632,0.0003381904,0.000151414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009401868,"about_ca_system_score_gemma":0.0001267475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004317152,"about_ca_topic_score_gemma":0.000609172,"domain_scores_codex":[0.999899,0.00002359202,0.000009583154,0.00001512013,0.0000292958,0.00002333863],"domain_scores_gemma":[0.9999365,0.00001553233,0.00001579849,0.00001103817,0.00001270732,0.00000837809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005302645,0.0002023953,0.001148563,0.0001281042,0.00002247432,0.0003157598,0.00005870718,0.00006688108,0.9903538,0.00006505386,0.0001975848,0.00691025],"study_design_scores_gemma":[0.00005589332,0.003030191,0.01314835,0.00001283866,0.00003636645,0.0007930562,0.00006597176,0.000530924,0.9793816,0.00007555223,0.002865672,0.000003670105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910939,0.005769106,0.001284683,0.0001872438,0.00005132555,0.00003218426,0.0001187642,0.00002212142,0.001440746],"genre_scores_gemma":[0.9960527,0.001838159,0.0004258882,0.0001092984,0.00001498626,0.00001598334,0.0001630829,0.000003242784,0.001376676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00101437,"threshold_uncertainty_score":0.003393471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03797316754298063,"score_gpt":0.2850244302345543,"score_spread":0.2470512626915737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}