{"id":"W2901854852","doi":"10.1038/s41564-018-0293-5","title":"An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread","year":2018,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; University Health Network; St. Michael's Hospital; Princess Margaret Cancer Centre; Hospital for Sick Children","funders":"","keywords":"ATG16L1; Cell biology; Autophagy; Cell membrane; Biology; Listeria monocytogenes; Membrane; Chemistry; Biochemistry; Bacteria; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000170035,0.0003095287,0.0004500499,0.0001369462,0.0001210423,0.0000204819,0.0001907178,0.00078061,0.000253148],"category_scores_gemma":[0.0000297208,0.0002449594,0.0001039196,0.0001270137,0.0001835118,0.00005907494,0.00007692405,0.0004057328,0.0001616573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003917942,"about_ca_system_score_gemma":0.0001054155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001576282,"about_ca_topic_score_gemma":0.00004448857,"domain_scores_codex":[0.9984283,0.0001209194,0.0002698789,0.0006907,0.00006843099,0.0004217516],"domain_scores_gemma":[0.9988441,0.0000568655,0.0000957083,0.0005789162,0.0001484663,0.0002759053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001000729,0.0003570565,0.00122746,0.00009749245,0.00007714276,0.0001155476,0.0005776206,3.747924e-7,0.9939317,0.00003359329,0.001255976,0.001325371],"study_design_scores_gemma":[0.002003725,0.00216885,0.001773061,0.00004553578,0.0000867283,0.0003349992,0.00007068913,0.00002768127,0.9654955,0.00003213028,0.02770114,0.0002599851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933605,0.003354458,0.00001351336,0.0003546904,0.0006158556,0.0006557571,0.0001358499,0.0002207285,0.001288602],"genre_scores_gemma":[0.9927399,0.0001327857,0.001749453,0.002831748,0.0006430958,0.00002246784,0.0001937504,0.0000495843,0.001637261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02843616,"threshold_uncertainty_score":0.9989155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057123845117661,"score_gpt":0.273939398089731,"score_spread":0.2633681596385544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}