{"id":"W2901899645","doi":"10.1002/cbic.201800616","title":"Influence of Linker Length on Ligase‐Catalyzed Oligonucleotide Polymerization","year":2018,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Linker; Oligonucleotide; DNA ligase; Combinatorial chemistry; Chemistry; DNA; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009259363,0.0001619368,0.0001640188,0.000056497,0.00005987421,0.000009034226,0.0001719916,0.0001614135,0.000002699597],"category_scores_gemma":[0.0001441677,0.0001464238,0.00009063849,0.0001927006,0.0002676363,0.000004194903,0.00007637462,0.00006118209,0.00001147578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000996742,"about_ca_system_score_gemma":0.0000321182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008184975,"about_ca_topic_score_gemma":0.000002903168,"domain_scores_codex":[0.9990945,0.00001765718,0.0002285044,0.0003460513,0.0001274244,0.0001858159],"domain_scores_gemma":[0.9991156,0.000007675751,0.0001483957,0.0004805147,0.0001856933,0.00006208043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000760328,0.00006072157,0.0002504949,0.00000962383,0.00003657511,5.612315e-7,0.00001661222,0.000006283067,0.9977192,0.00005295709,0.0003220648,0.001448866],"study_design_scores_gemma":[0.0001960496,0.0002501683,0.0009935538,0.00003686648,0.00002207004,0.000003834037,0.00001512772,0.00002116952,0.9965122,0.00003100612,0.001744478,0.0001735078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978979,0.00007286602,0.0002088794,0.0001064278,0.00002413408,0.00008117472,0.00001358029,0.0000440108,0.001551047],"genre_scores_gemma":[0.9976107,0.00008007819,0.001303925,0.0003310569,0.0002482103,0.00000385542,0.0001248965,0.00002153656,0.0002757144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001422413,"threshold_uncertainty_score":0.5970988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006206160417073457,"score_gpt":0.2564997166459129,"score_spread":0.2502935562288395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}