{"id":"W2901939101","doi":"10.1186/s13643-018-0854-y","title":"Herceptin® (trastuzumab) in HER2-positive early breast cancer: a systematic review and cumulative network meta-analysis","year":2018,"lang":"en","type":"review","venue":"Systematic Reviews","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa; Ottawa Public Health; St. Michael's Hospital; Roche (Canada)","funders":"F. Hoffmann-La Roche","keywords":"Medicine; Trastuzumab; Oncology; Internal medicine; Breast cancer; Meta-analysis; Anthracycline; Randomized controlled trial; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0216477,0.002506659,0.01041376,0.0078987,0.0004860844,0.002443762,0.002063679,0.001581045,0.003662685],"category_scores_gemma":[0.04659174,0.001062067,0.02919424,0.008224662,0.0004735308,0.001503211,0.001553166,0.001650269,0.0002995398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002598643,"about_ca_system_score_gemma":0.003570352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008917185,"about_ca_topic_score_gemma":0.01945289,"domain_scores_codex":[0.9863201,0.008675246,0.002397964,0.001109079,0.001158698,0.0003388246],"domain_scores_gemma":[0.9670665,0.02730378,0.00316668,0.0007404018,0.001461978,0.0002604742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001239326,0.00003383453,0.006094075,0.2874953,0.6823145,0.0001288502,0.00009226846,0.001900595,0.0001558509,0.0003445955,0.00116895,0.01903181],"study_design_scores_gemma":[0.0003652123,0.0001486327,0.003807496,0.02583225,0.965707,0.00009127202,0.00003790052,0.000702557,0.0000831885,0.0006016602,0.002598865,0.00002401733],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004514269,0.9921718,0.001166354,0.000373327,0.0001095324,0.0002928204,0.0009355735,0.00002744637,0.0004088639],"genre_scores_gemma":[0.255321,0.7342796,0.004945178,0.001289328,0.00028995,0.001729161,0.001657905,0.00004535761,0.0004426232],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0216477,"threshold_uncertainty_score":0.1144853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2706733704397618,"score_gpt":0.4849040559417607,"score_spread":0.2142306855019989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}