{"id":"W2901983772","doi":"10.1002/2211-5463.12566","title":"C/<scp>EBP</scp>β and <scp>YY</scp>1 bind and interact with Smad3 to modulate lipopolysaccharide‐induced amelotin gene transcription in mouse gingival epithelial cells","year":2018,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science; Nihon University","keywords":"Chromatin immunoprecipitation; Transcription factor; Ccaat-enhancer-binding proteins; Luciferase; Transcription (linguistics); Molecular biology; Chemistry; Junctional epithelium; Promoter; Lipopolysaccharide; Cell biology; Gene expression; Messenger RNA; Gene; Nuclear protein; Biology; Immunology; Epithelium; Biochemistry; Genetics; Transfection","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001753701,0.0005048181,0.0002367652,0.0003521103,0.0002947527,0.0002427505,0.0001571149,0.0002360971,0.0029266],"category_scores_gemma":[0.0001216654,0.0002355208,0.0003376574,0.000169142,0.0003290511,0.0001567538,0.000287483,0.0006912164,0.0006982088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003257782,"about_ca_system_score_gemma":0.000252797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008164622,"about_ca_topic_score_gemma":0.001496371,"domain_scores_codex":[0.9997774,0.00003003364,0.0000147346,0.00004223186,0.00005950298,0.00007613233],"domain_scores_gemma":[0.9998933,0.00001449594,0.00003145787,0.000008157314,0.000009964922,0.00004249197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001043937,0.00001922445,0.0001068071,0.00003142026,0.000003840917,0.00002477144,0.000007535572,0.00002794155,0.9992486,0.00004287459,0.00003410367,0.0003485817],"study_design_scores_gemma":[0.00007009105,0.0001958049,0.01985578,0.00002088701,0.00002077972,0.0003138368,0.00006592896,0.001439153,0.9740103,0.00009338243,0.003906204,0.000007780218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989033,0.003302106,0.004390102,0.0002574061,0.00006535736,0.00004662842,0.0007583001,0.00007846579,0.002068685],"genre_scores_gemma":[0.9861801,0.001971024,0.00333008,0.0002125777,0.00004151709,0.0001453713,0.001688935,0.00004538372,0.006384936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0029266,"threshold_uncertainty_score":0.009790421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01322073082681933,"score_gpt":0.2420757151796952,"score_spread":0.2288549843528759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}