{"id":"W2901983772","doi":"10.1002/2211-5463.12566","title":"C/<scp>EBP</scp>β and <scp>YY</scp>1 bind and interact with Smad3 to modulate lipopolysaccharide‐induced amelotin gene transcription in mouse gingival epithelial cells","year":2018,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science; Nihon University","keywords":"Chromatin immunoprecipitation; Transcription factor; Ccaat-enhancer-binding proteins; Luciferase; Transcription (linguistics); Molecular biology; Chemistry; Junctional epithelium; Promoter; Lipopolysaccharide; Cell biology; Gene expression; Messenger RNA; Gene; Nuclear protein; Biology; Immunology; Epithelium; Biochemistry; Genetics; Transfection","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002217414,0.0002859344,0.0002589905,0.0001277564,0.0001287572,0.000291191,0.0003139403,0.0001537622,0.000008140332],"category_scores_gemma":[0.00004171467,0.0002510157,0.00003610621,0.000125289,0.0001165525,0.00004314195,0.0003287384,0.0001090888,0.00004313268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000196382,"about_ca_system_score_gemma":0.00005053907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003055391,"about_ca_topic_score_gemma":0.000663778,"domain_scores_codex":[0.9985426,0.00005351866,0.0002656256,0.0006132277,0.0001354937,0.0003895301],"domain_scores_gemma":[0.9994249,0.00001784003,0.00008671104,0.0002332997,0.00005996911,0.0001772525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007308472,0.00006282049,0.008800991,0.00001471339,0.00004586721,0.000009727633,0.0008827159,0.000002324289,0.9877926,0.0000149198,0.0004887893,0.001811476],"study_design_scores_gemma":[0.001142294,0.0006716656,0.02653537,0.00004657406,0.0000154212,0.000022651,0.0003874891,0.00003619382,0.9640963,0.00002450358,0.006900766,0.0001207819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981099,0.0001009602,0.0001077497,0.00007520575,0.0002301413,0.0005336754,0.00004904304,0.00001524477,0.000778014],"genre_scores_gemma":[0.9917185,0.0001483437,0.001315369,0.0003431199,0.0001921577,0.00003051613,0.00007974504,0.00004177585,0.006130528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02369628,"threshold_uncertainty_score":0.9999942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01322073082681933,"score_gpt":0.2420757151796952,"score_spread":0.2288549843528759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}