{"id":"W2902119334","doi":"10.1097/mph.0000000000001355","title":"Genetic Profile and Microsatellite Instability in a Case of Secondary Esophageal Squamous Cell Carcinoma 12 Years After Allogeneic Hematopoietic Stem Cell Transplantation for Aplastic Anemia","year":2018,"lang":"en","type":"article","venue":"Journal of Pediatric Hematology/Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Microsatellite instability; DNA mismatch repair; Aplastic anemia; Transplantation; Cancer research; Hematopoietic stem cell transplantation; Stem cell; Haematopoiesis; Biology; Medicine; Oncology; Immunology; Internal medicine; Microsatellite; Gene; DNA repair; Genetics; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002037832,0.0005097939,0.0006248432,0.001420576,0.001224739,0.000494872,0.0003433677,0.00139351,0.001127143],"category_scores_gemma":[0.001051864,0.0003298196,0.0005948194,0.0006435571,0.0004828573,0.0003561817,0.0004906981,0.001040207,0.0003807819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003859361,"about_ca_system_score_gemma":0.0003690218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002372456,"about_ca_topic_score_gemma":0.002201158,"domain_scores_codex":[0.9997635,0.00002734653,0.00002934022,0.00005519328,0.00004115718,0.00008351982],"domain_scores_gemma":[0.9991701,0.0001520704,0.0001731329,0.00004026345,0.0000728507,0.0003915943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001279893,0.00008461304,0.1085302,0.00002380957,0.000019937,0.8840318,0.0005983643,0.00008807497,0.00431854,0.00006107923,0.0001110282,0.002004576],"study_design_scores_gemma":[0.00001456006,0.000469156,0.1159182,0.00001175476,0.00005648574,0.8804034,0.0003562758,0.0003204608,0.001704922,0.000061401,0.0006661092,0.00001725834],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983737,0.0004624787,0.0003115405,0.0001399615,0.00001813999,0.00001745301,0.00006795758,0.00001622878,0.0005924763],"genre_scores_gemma":[0.999049,0.0002406905,0.0001786974,0.00007209946,0.0000398146,0.000005493762,0.00008107474,0.000005790005,0.000327405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002372456,"threshold_uncertainty_score":0.00471729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006939049179228929,"score_gpt":0.2420307830994692,"score_spread":0.2350917339202402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}