{"id":"W2902130013","doi":"10.1016/j.celrep.2018.10.105","title":"Critical Role of Regulatory T Cells in the Latency and Stress-Induced Reactivation of HSV-1","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Herpes simplex virus; Latency (audio); Immune system; HSL and HSV; Infectivity; Biology; CD8; Viral replication; Virology; Immunology; Virus; Cell biology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000592403,0.0003740999,0.0002546709,0.0003354713,0.0003006172,0.0005289569,0.0003400521,0.0004459859,0.003137747],"category_scores_gemma":[0.0004773531,0.0001070944,0.0002621868,0.00008643731,0.0006680205,0.0004521967,0.0002570506,0.000943266,0.0003684339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001731479,"about_ca_system_score_gemma":0.000488861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001389616,"about_ca_topic_score_gemma":0.0002168935,"domain_scores_codex":[0.9997328,0.00008830059,0.00002023522,0.00004303882,0.00003611446,0.00007944624],"domain_scores_gemma":[0.999749,0.00005756628,0.00004257438,0.00003566275,0.00003857663,0.00007655667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002052661,0.0003149603,0.003130731,0.0003487035,0.00002663246,0.001460116,0.0002442058,0.0003277255,0.9364996,0.008664678,0.0008333859,0.04609643],"study_design_scores_gemma":[0.000938557,0.00645202,0.05173828,0.0003838797,0.0003403322,0.009062698,0.001178578,0.004107902,0.8446298,0.01870534,0.06240309,0.00005955693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.945656,0.02926894,0.007846931,0.001463141,0.001020708,0.0001205216,0.0002204424,0.000236713,0.01416668],"genre_scores_gemma":[0.9948879,0.0015157,0.001445546,0.0001432718,0.0001650366,0.00003656059,0.00004482955,0.00001098747,0.001750211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003137747,"threshold_uncertainty_score":0.0104968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300485274839718,"score_gpt":0.2770494978349644,"score_spread":0.2640446450865672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}