{"id":"W2902408864","doi":"10.1093/ofid/ofy209.022","title":"152. Protective Antibody Levels 7.5 Years After Primary Vaccination in Adolescence With a Recombinant, 4-Component, Meningococcal Serogroup B Vaccine (4CMenB) and Response to a Booster Dose in Adolescents and Young Adults: Phase IIIb Clinical Findings","year":2018,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; Canadian Rheumatology Association","funders":"GlaxoSmithKline; Pfizer","keywords":"Medicine; Vaccination; Booster dose; Immunogenicity; Meningococcal vaccine; Pediatrics; Antibody; Booster (rocketry); Immunology; Immunization","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006065387,0.0003010549,0.0005095733,0.0003915453,0.0001949655,0.0001527324,0.0001715174,0.0002057383,0.00009307105],"category_scores_gemma":[0.0001773815,0.0002661046,0.00004715627,0.0004099791,0.0000889032,0.000664408,0.0004571166,0.0003114337,0.00003260347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001375326,"about_ca_system_score_gemma":0.00008592688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006890718,"about_ca_topic_score_gemma":0.002299753,"domain_scores_codex":[0.997672,0.0005894394,0.0005240667,0.0007091629,0.00003605169,0.0004692829],"domain_scores_gemma":[0.9992962,0.00008212142,0.000147453,0.00025986,0.0001108461,0.0001034752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03873282,0.001787843,0.9268863,0.0000520641,0.00005480864,0.00002247332,0.0007240913,1.736525e-7,0.0182102,0.000008152962,0.00009286209,0.01342825],"study_design_scores_gemma":[0.02010597,0.003863069,0.9734168,0.001063524,0.00004336131,0.0001292691,0.000190202,0.000007177097,0.0004280029,0.00005087803,0.0003482976,0.0003534516],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965251,0.0001965117,0.00006010994,0.0001888302,0.0003923964,0.002475568,0.00007302887,0.00004966001,0.0000387688],"genre_scores_gemma":[0.99909,0.00003827392,0.0000263737,0.0002678933,0.0000323739,0.0004173461,0.00004033396,0.00003312562,0.00005434825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04653054,"threshold_uncertainty_score":0.9999791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178211040696629,"score_gpt":0.31352224807076,"score_spread":0.3017401376637937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}