{"id":"W2902483275","doi":"10.1021/acs.orglett.8b03148","title":"Soft-enolization Baker–Venkataraman Rearrangement Enabled Total Synthesis of Dirchromones and Related 2-Substituted Chromones","year":2018,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis of Organic Compounds","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Chicoutimi","funders":"Natural Sciences and Engineering Research Council of Canada; Institute of Cancer Research; Université du Québec à Chicoutimi","keywords":"Chemistry; Keto–enol tautomerism; Organic chemistry; Medicinal chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001709575,0.0003895827,0.0002163325,0.0002640361,0.0001744764,0.0001936047,0.0002902237,0.0001981978,0.002909781],"category_scores_gemma":[0.0001366446,0.0001480213,0.0002010672,0.0002125738,0.0002622478,0.0003825976,0.000395973,0.0005224414,0.0007508633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002637229,"about_ca_system_score_gemma":0.0004217548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005344452,"about_ca_topic_score_gemma":0.002030371,"domain_scores_codex":[0.9998878,0.00001456672,0.000007464579,0.00002453594,0.00001944901,0.00004617544],"domain_scores_gemma":[0.9999415,0.00001099354,0.00001262917,0.00001058606,0.00001092227,0.00001328763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001654584,0.00006529861,0.0002380153,0.0003829063,0.00002744536,0.0006938856,0.000188729,0.001724746,0.9576011,0.006489681,0.0006787885,0.03174401],"study_design_scores_gemma":[0.00004337926,0.0009096898,0.001514321,0.00002909322,0.0000310119,0.0007562775,0.0001013951,0.001331162,0.9703396,0.0009287245,0.02396203,0.00005336192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9173377,0.005580002,0.04456974,0.0003049611,0.0001711834,0.0002407986,0.000938972,0.0003509298,0.03050581],"genre_scores_gemma":[0.9764312,0.002145004,0.01212939,0.00008605943,0.00001141169,0.0000829151,0.0003872809,0.00003439445,0.00869235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002909781,"threshold_uncertainty_score":0.009734154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008921591381819713,"score_gpt":0.2195565974605923,"score_spread":0.2106350060787726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}