{"id":"W2902531712","doi":"10.1111/febs.14710","title":"The structure of <i>Legionella</i> effector protein LpnE provides insights into its interaction with Oculocerebrorenal syndrome of Lowe (<scp>OCRL</scp>) protein","year":2018,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Western Economic Diversification Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Research Council Canada; Canada Foundation for Innovation; University of Saskatchewan","keywords":"Legionella pneumophila; Effector; Cell biology; Tetratricopeptide; Biology; Secretion; Transport protein; Protein–protein interaction; Microbiology; Chemistry; Bacteria; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007452381,0.0003489459,0.0003171167,0.0001540358,0.0003130799,0.0004462702,0.0004057355,0.0005221472,0.001701699],"category_scores_gemma":[0.0001529384,0.0001554529,0.0002919256,0.0002099323,0.0002071275,0.0004128341,0.0002027063,0.0008418615,0.0004540534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009617538,"about_ca_system_score_gemma":0.0004140571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003050363,"about_ca_topic_score_gemma":0.003501207,"domain_scores_codex":[0.9999515,0.000006748619,0.000002944,0.00001325283,0.00001512625,0.00001037719],"domain_scores_gemma":[0.9999402,0.000009747696,0.00001601475,0.00000357505,0.000009187431,0.00002136431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004442579,0.0001627623,0.004646009,0.000332072,0.00004567036,0.001481169,0.0002444207,0.003327454,0.9800538,0.001627762,0.001937978,0.005696567],"study_design_scores_gemma":[0.000285077,0.000854201,0.06951756,0.0001704729,0.0002205429,0.004825994,0.001221764,0.07509719,0.7541531,0.001955328,0.09155024,0.0001485304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988713,0.003371736,0.002788588,0.0006775903,0.00006479537,0.00001948726,0.0007834169,0.0001666173,0.003414739],"genre_scores_gemma":[0.984498,0.002089943,0.005228401,0.0002542755,0.000020015,0.0000169118,0.003226933,0.00003405878,0.004631407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003050363,"threshold_uncertainty_score":0.006978035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006688749080421484,"score_gpt":0.2417934355220618,"score_spread":0.2351046864416403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}