{"id":"W2902531712","doi":"10.1111/febs.14710","title":"The structure of <i>Legionella</i> effector protein LpnE provides insights into its interaction with Oculocerebrorenal syndrome of Lowe (<scp>OCRL</scp>) protein","year":2018,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Western Economic Diversification Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Research Council Canada; Canada Foundation for Innovation; University of Saskatchewan","keywords":"Legionella pneumophila; Effector; Cell biology; Tetratricopeptide; Biology; Secretion; Transport protein; Protein–protein interaction; Microbiology; Chemistry; Bacteria; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002494712,0.0002170012,0.0002391027,0.0001004682,0.0003122138,0.00007849399,0.0004102576,0.0001643654,0.00001094232],"category_scores_gemma":[0.0002397088,0.0001240837,0.0001112274,0.0002198596,0.0003948389,0.00002831317,0.0001278187,0.0004076903,0.000008023717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003409947,"about_ca_system_score_gemma":0.0002897582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003376381,"about_ca_topic_score_gemma":0.0001152318,"domain_scores_codex":[0.9983368,0.0002020727,0.0003881867,0.00027013,0.0004707447,0.0003320968],"domain_scores_gemma":[0.9984041,0.00003825715,0.0004345083,0.0003073735,0.0006739586,0.0001417998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003961698,0.00006857259,0.0004694504,0.0001304124,0.0001638807,0.00001936953,0.0002270961,0.00001269738,0.9966099,0.00004273838,0.001172532,0.0006872145],"study_design_scores_gemma":[0.0008353149,0.002905547,0.0007868657,0.0003212604,0.00002046989,0.0005185985,0.0001763566,0.00004835534,0.9825338,0.0002845213,0.01148089,0.0000880862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977145,0.0007283832,0.0003571697,0.0001635625,0.0001396087,0.000688101,0.000007375201,0.000006036913,0.0001953258],"genre_scores_gemma":[0.9982473,0.00006527024,0.0003400313,0.00002432871,0.0005237812,0.00001498587,0.00001365031,0.00003082913,0.0007398328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01407613,"threshold_uncertainty_score":0.5059984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006688749080421484,"score_gpt":0.2417934355220618,"score_spread":0.2351046864416403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}