{"id":"W2902603379","doi":"10.14814/phy2.13897","title":"Ski drives an acute increase in MMP-9 gene expression and release in primary cardiac myofibroblasts","year":2018,"lang":"en","type":"article","venue":"Physiological Reports","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research; National Institutes of Health; Research Manitoba; Heart and Stroke Foundation of Canada","keywords":"Myofibroblast; Extracellular matrix; Cardiac fibrosis; Focal adhesion; Fibronectin; Fibrosis; Paxillin; Cell biology; SMAD; Extracellular; Matrix metalloproteinase; Cancer research; Chemistry; Pathology; Biology; Transforming growth factor; Medicine; Signal transduction; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003224678,0.0001979868,0.0006221906,0.000102568,0.0000563977,0.00001882022,0.00003901054,0.0001808972,0.00002025633],"category_scores_gemma":[0.0001745415,0.0001345127,0.0001279244,0.0001680281,0.0001698466,0.0001410074,0.0001684911,0.0002304207,0.000003957241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006703232,"about_ca_system_score_gemma":0.00006673712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001109415,"about_ca_topic_score_gemma":0.000002438963,"domain_scores_codex":[0.9982154,0.0001254445,0.0004743733,0.0006376171,0.0002262736,0.0003208302],"domain_scores_gemma":[0.9990723,0.00004763073,0.0001242621,0.0004227786,0.00006291748,0.0002700846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003883851,0.0001964609,0.04963771,0.00003153521,0.00001421308,0.0004804243,0.000124952,0.00002557356,0.9468625,0.000004564155,0.0001599824,0.002073737],"study_design_scores_gemma":[0.0005247065,0.0005854,0.9650438,0.0002893066,0.00003532233,0.0001629799,0.00003484369,0.0003168398,0.03213483,0.0005375518,0.0001370814,0.0001972788],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982121,0.0004036801,0.00001661273,0.00004805605,0.0001295616,0.000337913,0.000004463308,0.00005088868,0.0007967179],"genre_scores_gemma":[0.9966723,0.0003217406,0.002233127,0.0002271595,0.0003763729,0.00002447731,0.00008332488,0.0000181505,0.00004335406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9154062,"threshold_uncertainty_score":0.5485267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01505063293214015,"score_gpt":0.2760957327728854,"score_spread":0.2610450998407453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}