{"id":"W2902697340","doi":"10.1111/bjd.17454","title":"Safety of guselkumab in patients with moderate‐to‐severe psoriasis treated through 100 weeks: a pooled analysis from the randomized <scp>VOYAGE</scp> 1 and <scp>VOYAGE</scp> 2 studies","year":2018,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Janssen Research and Development","keywords":"Medicine; Adalimumab; Adverse effect; Randomized controlled trial; Placebo; Clinical trial; Psoriasis; Internal medicine; Dermatology; Pathology; Alternative medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01653171,0.001380774,0.0051762,0.001295464,0.0003090217,0.001606724,0.0007694689,0.001179909,0.002412365],"category_scores_gemma":[0.0109506,0.0008249772,0.01739354,0.00133353,0.0004956817,0.0009962028,0.0008144589,0.001521995,0.0002560592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006613387,"about_ca_system_score_gemma":0.0007502543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005690961,"about_ca_topic_score_gemma":0.001334228,"domain_scores_codex":[0.9901497,0.006380151,0.001245671,0.001063548,0.0008973019,0.0002635865],"domain_scores_gemma":[0.9886817,0.005272719,0.004134782,0.001003441,0.0005955306,0.0003119047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.5742621,0.0007500604,0.04270509,0.008912388,0.3274274,0.00009730239,0.0001361608,0.002051915,0.00330468,0.0001079421,0.001084932,0.03916003],"study_design_scores_gemma":[0.1926178,0.05308026,0.2290179,0.001363664,0.5132834,0.0004390973,0.0001599722,0.002787468,0.002301593,0.0007880408,0.004011311,0.0001493797],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8518471,0.1341575,0.004971256,0.000436326,0.0003208723,0.001372467,0.00435813,0.0001712151,0.002365093],"genre_scores_gemma":[0.9870459,0.008780369,0.001008741,0.0002742175,0.0001686321,0.0006244401,0.001703833,0.0000274856,0.0003663562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01653171,"threshold_uncertainty_score":0.08742905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088767086225184,"score_gpt":0.2330105187170785,"score_spread":0.2221228478548266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}