{"id":"W2902697340","doi":"10.1111/bjd.17454","title":"Safety of guselkumab in patients with moderate‐to‐severe psoriasis treated through 100 weeks: a pooled analysis from the randomized <scp>VOYAGE</scp> 1 and <scp>VOYAGE</scp> 2 studies","year":2018,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research","funders":"Janssen Research and Development","keywords":"Medicine; Adalimumab; Adverse effect; Randomized controlled trial; Placebo; Clinical trial; Psoriasis; Internal medicine; Dermatology; Pathology; Alternative medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005305239,0.0004648362,0.00279118,0.0004122049,0.0003999962,0.00005463947,0.0004586776,0.0004476337,0.00006125648],"category_scores_gemma":[0.001297521,0.0003383901,0.00044461,0.0009164551,0.000905917,0.0002965451,0.0001556418,0.0004109102,0.00002622805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007932816,"about_ca_system_score_gemma":0.000139488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009135108,"about_ca_topic_score_gemma":0.001511543,"domain_scores_codex":[0.9951478,0.002057318,0.001504167,0.0004973149,0.0001720939,0.000621326],"domain_scores_gemma":[0.9942826,0.003363354,0.001126492,0.0003665998,0.0007825343,0.00007841346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06584829,0.003292015,0.7065166,0.0001105684,0.1359376,0.001862217,0.03312994,0.0001967306,0.001817281,0.0002084007,0.0265577,0.02452267],"study_design_scores_gemma":[0.4259309,0.001605583,0.5087288,0.0009394871,0.02342532,0.004513299,0.00812553,0.00002806708,0.02236185,0.001373498,0.00257254,0.0003950928],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753498,0.02253717,0.0002602366,0.0001965227,0.0003925603,0.0006645549,0.0002850228,0.00002602224,0.0002880499],"genre_scores_gemma":[0.9947446,0.003949462,0.0005257057,0.0002508697,0.00006938523,0.0000404643,0.0001400942,0.00003748835,0.0002419591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3600826,"threshold_uncertainty_score":0.9999068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088767086225184,"score_gpt":0.2330105187170785,"score_spread":0.2221228478548266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}