{"id":"W2902751959","doi":"10.3389/fgene.2018.00595","title":"The Multiples Fates of the Flavivirus RNA Genome During Pathogenesis","year":2018,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Institut national de la recherche scientifique; Fonds de recherche du Québec – Nature et technologies; Université de Montréal; Armand-Frappier Foundation; McGill University","keywords":"Flavivirus; RNA; Virology; Biology; Dengue fever; Viral replication; Viral life cycle; Viral evolution; Interferon; Gene; Computational biology; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000421424,0.0003059084,0.0002804197,0.0004347814,0.0004911424,0.001044813,0.0002518614,0.0007984233,0.0009380267],"category_scores_gemma":[0.00035665,0.0002650589,0.0003351788,0.0001467808,0.0004929429,0.001381013,0.0007870215,0.0008577695,0.00079557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005975765,"about_ca_system_score_gemma":0.0003044884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00043417,"about_ca_topic_score_gemma":0.0003927418,"domain_scores_codex":[0.9996197,0.00005771621,0.00001719587,0.0001117027,0.0001160052,0.0000777055],"domain_scores_gemma":[0.9998173,0.00002758216,0.00004557398,0.0000245279,0.0000479519,0.00003720342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001021236,0.00003189426,0.004408899,0.0001413317,0.00000983746,0.0004491468,0.0003498234,0.0002337192,0.9715803,0.002812055,0.000276265,0.01960454],"study_design_scores_gemma":[0.00003242192,0.0009567852,0.09456117,0.0004163897,0.000102497,0.005827315,0.002413884,0.006789863,0.8022201,0.01441225,0.07216089,0.0001063964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8907175,0.05079715,0.03852802,0.001170934,0.0002760673,0.0001144655,0.0003506779,0.0005558745,0.0174893],"genre_scores_gemma":[0.9822734,0.006360055,0.00544222,0.0001827597,0.00006527625,0.0000434253,0.0002489671,0.00004082348,0.005343146],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001044813,"threshold_uncertainty_score":0.004335761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01837675331689236,"score_gpt":0.2781747484751493,"score_spread":0.2597979951582569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}