{"id":"W2902755567","doi":"10.1371/journal.pone.0207303","title":"Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; Queen's University; Queen's University Belfast","keywords":"Mesenchymal stem cell; In vitro; Osteoblast; In vivo; Biology; Cell culture; Microbiology; Cell biology; Chemistry; Biochemistry; Biotechnology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758413,0.0001234864,0.0002114718,0.00001151038,0.0001509995,0.00004113717,0.0003322846,0.00009295348,0.0005491244],"category_scores_gemma":[0.0001128081,0.00004770427,0.0000714753,0.0002305029,0.0001433905,0.0001192064,0.0001868277,0.0001275372,0.00001128449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002529384,"about_ca_system_score_gemma":0.000008582826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00135366,"about_ca_topic_score_gemma":0.001819152,"domain_scores_codex":[0.9989682,0.00008108607,0.0001716418,0.0002758565,0.0002488875,0.0002543654],"domain_scores_gemma":[0.9992388,0.0003492132,0.0001298023,0.00009179996,0.0001404726,0.00004993181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001710139,0.0004761411,0.01321978,0.000004377969,0.00006673223,8.861848e-7,0.00004472616,2.377783e-7,0.969006,0.000003858974,0.00004026992,0.01696598],"study_design_scores_gemma":[0.0002071216,0.0002564528,0.5510555,0.00002124123,0.00003546266,3.078197e-7,0.000128804,0.000191583,0.4475935,0.0003337916,0.00008651612,0.00008968974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974457,0.00002597892,0.00006023009,0.001600928,0.0000563127,0.0003867282,0.00008752922,0.00003145225,0.0003051166],"genre_scores_gemma":[0.9976179,0.00001306561,0.001429297,0.0001220201,0.0006399597,0.00002008997,0.0000497001,0.000002116092,0.0001058689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5378357,"threshold_uncertainty_score":0.6012527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07371488829727753,"score_gpt":0.2361733516238682,"score_spread":0.1624584633265907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}