{"id":"W2902818589","doi":"10.1002/btpr.2761","title":"Fluorescence‐based real time monitoring and diagnostics of recombinant <i>Pichia pastoris</i> cultivations in a bioreactor","year":2018,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Pichia pastoris; Bioreactor; Recombinant DNA; Pichia; Chemistry; Fluorescence; Chromatography; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003820243,0.0003943592,0.0004065121,0.000293714,0.0001544676,0.0004644222,0.0003726275,0.0003608024,0.0002146711],"category_scores_gemma":[0.0004194231,0.0001800649,0.0002899167,0.0003461297,0.0002310463,0.0003347554,0.0002689817,0.0004864425,0.0001979538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004431633,"about_ca_system_score_gemma":0.0002544704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001223477,"about_ca_topic_score_gemma":0.001024814,"domain_scores_codex":[0.9995419,0.00005833189,0.00002726995,0.0001438396,0.0001885183,0.00004024242],"domain_scores_gemma":[0.999832,0.00004545811,0.000050379,0.00002038703,0.0000373622,0.00001431594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003355414,0.000009175537,0.0003624266,0.00001836299,0.000002927374,0.00001716765,0.00001511778,0.0001486733,0.9966115,0.00002685033,0.00002415505,0.002730063],"study_design_scores_gemma":[0.000003152861,0.00005822015,0.001986313,0.00000259673,0.000006931893,0.00007846931,0.00001405708,0.003707296,0.9936249,0.00002775419,0.0004821023,0.000008020168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9000212,0.001260665,0.09532078,0.0002028391,0.00003628256,0.00006955964,0.000626195,0.001181905,0.0012805],"genre_scores_gemma":[0.8990588,0.001223541,0.09785385,0.0001058906,0.00001652825,0.00007546813,0.0004791231,0.00008266111,0.001104178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001223477,"threshold_uncertainty_score":0.003215373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008846228318369254,"score_gpt":0.2677113572337541,"score_spread":0.2588651289153849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}