{"id":"W2902848414","doi":"10.3389/fgene.2018.00529","title":"Fragile X Associated Primary Ovarian Insufficiency (FXPOI): Case Report and Literature Review","year":2018,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Azrieli Foundation","keywords":"Fragile X syndrome; Premature ovarian failure; Medicine; Hypergonadotropic hypogonadism; Premature ovarian insufficiency; Infertility; Disease; Pediatrics; Anxiety; Depression (economics); Hypoestrogenism; Menopause; Psychiatry; Gynecology; Internal medicine; Pregnancy; Hormone; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003240955,0.001349342,0.001439696,0.007601631,0.001182861,0.001397709,0.001656783,0.002621435,0.004699327],"category_scores_gemma":[0.001385562,0.0004999978,0.0007638922,0.005660233,0.00128873,0.002714947,0.001244179,0.00173528,0.001728574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006675791,"about_ca_system_score_gemma":0.001271511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00148397,"about_ca_topic_score_gemma":0.001769838,"domain_scores_codex":[0.9995409,0.0000587973,0.0001654908,0.0001000257,0.00007790045,0.00005689609],"domain_scores_gemma":[0.9989261,0.0003843089,0.0004168341,0.00004049678,0.0001082324,0.0001240318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00009599543,0.0002060367,0.0115757,0.01553657,0.0002305487,0.7019923,0.001219232,0.0005460568,0.002731692,0.002369816,0.0540516,0.2094444],"study_design_scores_gemma":[0.00001163097,0.00003603894,0.003742646,0.003884592,0.0001881889,0.925844,0.0006577998,0.0001049821,0.0002860317,0.0008770893,0.0643227,0.00004427791],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01409878,0.9732919,0.001130415,0.002627312,0.001297127,0.0001020584,0.000260875,0.00009862796,0.007092976],"genre_scores_gemma":[0.07993503,0.9067624,0.002166959,0.002787327,0.005556401,0.0000947608,0.0005473756,0.00003141804,0.00211837],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007601631,"threshold_uncertainty_score":0.01572078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01157114213536584,"score_gpt":0.2651564153803299,"score_spread":0.253585273244964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}