{"id":"W2902865577","doi":"10.3390/cancers10120477","title":"Screening BRCA1 and BRCA2 Mutation Carriers for Breast Cancer","year":2018,"lang":"en","type":"review","venue":"Cancers","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Mammography; Breast cancer; Observational study; Oncology; Magnetic resonance imaging; Stage (stratigraphy); Breast cancer screening; Cancer; Internal medicine; Gynecology; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000799835,0.0007230362,0.001663341,0.002107655,0.0002264348,0.0006606732,0.0008976014,0.0008787647,0.003532576],"category_scores_gemma":[0.002113194,0.000229293,0.001188841,0.001932551,0.0003066521,0.0006928698,0.0004435543,0.001300692,0.0007494258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005715406,"about_ca_system_score_gemma":0.001131965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001468978,"about_ca_topic_score_gemma":0.003255846,"domain_scores_codex":[0.999729,0.00006085873,0.0000486191,0.00004683946,0.00009278999,0.00002183041],"domain_scores_gemma":[0.9991249,0.0005557047,0.0001143576,0.00002018475,0.0001474503,0.00003734796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000129962,0.00005215882,0.0006761634,0.05558424,0.000611757,0.000134598,0.00003951573,0.000244005,0.0004511614,0.001344941,0.03036927,0.9103622],"study_design_scores_gemma":[0.00007725648,0.0002063523,0.00617033,0.04131692,0.002725772,0.003024761,0.0001081877,0.0001529906,0.000545478,0.003061248,0.9425758,0.00003480456],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007650843,0.9992924,0.00003371802,0.0001888089,0.00007191388,0.000002735613,0.00002325413,0.000003051407,0.0003076138],"genre_scores_gemma":[0.0006524691,0.998913,0.00006648536,0.0001282896,0.00004871521,0.000003916276,0.00003807922,6.692111e-7,0.0001483089],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003532576,"threshold_uncertainty_score":0.01181769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03352845659242609,"score_gpt":0.3480021272252624,"score_spread":0.3144736706328363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}