{"id":"W2902868244","doi":"10.1071/rdv31n1ab20","title":"20 Generation of myostatin knockout horse embryos using clustered regularly interspaced short palindromic repeats/CRISPR-associated gene 9 and somatic cell nuclear transfer","year":2018,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Artron Bioresearch (Canada)","funders":"","keywords":"Biology; CRISPR; Plasmid; Genetics; Molecular biology; Gene; Zinc finger nuclease; Guide RNA; Exon; Cas9; Genome editing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004926653,0.0003566297,0.0004298704,0.0004559439,0.0003058687,0.0003181497,0.0005619649,0.0005212523,0.004336733],"category_scores_gemma":[0.000169542,0.0003350839,0.000392912,0.000189591,0.0002540277,0.0002267115,0.0005188799,0.0006579994,0.001565608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003311571,"about_ca_system_score_gemma":0.0003408679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008576714,"about_ca_topic_score_gemma":0.002088174,"domain_scores_codex":[0.9996501,0.00004047163,0.00004709294,0.00006826322,0.0001483306,0.00004570855],"domain_scores_gemma":[0.999874,0.00002055798,0.00003268082,0.00001865705,0.00002027624,0.00003385074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006453835,0.00004636357,0.0001978623,0.0001092,0.000009302721,0.0002847372,0.00009372782,0.0001325195,0.9952939,0.0005805577,0.0002243898,0.00296293],"study_design_scores_gemma":[0.00005750483,0.0005971814,0.004099593,0.00004429442,0.00005125117,0.001177871,0.00007705387,0.003170731,0.9549676,0.0001828073,0.03554744,0.00002673394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8876748,0.00311915,0.0822328,0.0003509315,0.0003548972,0.001899687,0.004663554,0.00085688,0.01884732],"genre_scores_gemma":[0.8465465,0.003742172,0.07803063,0.000237042,0.00004554649,0.001341304,0.008529708,0.0004021099,0.06112492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004336733,"threshold_uncertainty_score":0.01450783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02624955243009703,"score_gpt":0.2753423953670063,"score_spread":0.2490928429369093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}