{"id":"W2902953998","doi":"10.1186/s13104-018-3955-8","title":"Isolation and characterization of camelid single-domain antibodies against HER2","year":2018,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Panning (audio); Ectodomain; Single-domain antibody; Recombinant DNA; Epitope; Antibody; Biology; Molecular biology; Flow cytometry; Epitope mapping; Virology; Computational biology; Immunology; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000211116,0.0004020214,0.0003387443,0.000593276,0.0002117874,0.0005102124,0.0004188606,0.0003717152,0.001071231],"category_scores_gemma":[0.0004009918,0.0001652651,0.0004674568,0.0002488704,0.0001419202,0.0002500213,0.0002970837,0.0005346849,0.0007355756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004810716,"about_ca_system_score_gemma":0.000125672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006336702,"about_ca_topic_score_gemma":0.0007928643,"domain_scores_codex":[0.999843,0.00002315516,0.000016595,0.00003811326,0.00003578341,0.00004333002],"domain_scores_gemma":[0.9998345,0.00002969405,0.00002465557,0.00002877716,0.0000435187,0.00003874802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005040037,0.00002947907,0.0004778421,0.00002558818,0.000007973872,0.00009186807,0.00002398502,0.00007212575,0.9968954,0.00006469116,0.0001388816,0.00212179],"study_design_scores_gemma":[0.0000937943,0.0009822937,0.03089488,0.000031715,0.00008946995,0.002010589,0.0001009064,0.003284057,0.9316066,0.0001485098,0.03073084,0.00002623074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823641,0.001692096,0.009533942,0.0002845526,0.0000796376,0.000245324,0.001854806,0.0001172155,0.003828367],"genre_scores_gemma":[0.9666755,0.001383437,0.01556955,0.0009551869,0.0001489963,0.0001549529,0.009907232,0.00007826053,0.00512686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001071231,"threshold_uncertainty_score":0.00358367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1348680258834679,"score_gpt":0.400091072457144,"score_spread":0.2652230465736761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}