{"id":"W2902953998","doi":"10.1186/s13104-018-3955-8","title":"Isolation and characterization of camelid single-domain antibodies against HER2","year":2018,"lang":"en","type":"article","venue":"BMC Research Notes","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Panning (audio); Ectodomain; Single-domain antibody; Recombinant DNA; Epitope; Antibody; Biology; Molecular biology; Flow cytometry; Epitope mapping; Virology; Computational biology; Immunology; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009534471,0.0001150383,0.0002523673,0.0003351953,0.0002228493,0.00004253361,0.00009608707,0.00008816615,0.0001206679],"category_scores_gemma":[0.0007753657,0.00009036548,0.00005211169,0.0004009093,0.0008706015,0.0001376493,0.000156683,0.0002266576,0.00006280727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000487925,"about_ca_system_score_gemma":0.0001703045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000220614,"about_ca_topic_score_gemma":0.00009418483,"domain_scores_codex":[0.9980676,0.0002287223,0.0002689403,0.0002733359,0.0007560222,0.0004053572],"domain_scores_gemma":[0.9982529,0.0005093432,0.00005818795,0.0002258001,0.0007872715,0.0001664942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005504904,0.00009029961,0.1959876,0.0002689604,0.00002313558,0.000006790164,0.0004608856,1.304822e-7,0.7941924,0.0004258336,0.00009534463,0.007898077],"study_design_scores_gemma":[0.0007454449,0.0013371,0.6814565,0.0003363771,0.000009207609,0.00002302598,0.0002339466,0.001543427,0.3073694,0.0006213477,0.006182143,0.0001421281],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941113,0.0002030958,0.0007137299,0.001221259,0.00005345412,0.0003801202,0.0000290434,0.00002304007,0.003264938],"genre_scores_gemma":[0.9946655,0.0003920288,0.003056405,0.00007201498,0.0005392748,0.00001061955,0.00009477173,0.00001934546,0.001150016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4868231,"threshold_uncertainty_score":0.3684997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1348680258834679,"score_gpt":0.400091072457144,"score_spread":0.2652230465736761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}