{"id":"W2902998154","doi":"10.1182/blood-2018-99-112697","title":"Three-Year Follow up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM)","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University; University of Calgary","funders":"","keywords":"Lenalidomide; Daratumumab; Medicine; Internal medicine; Dexamethasone; Oncology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008208975,0.001027194,0.003395468,0.000609262,0.001295713,0.002094835,0.0009802412,0.002406216,0.003227601],"category_scores_gemma":[0.005869193,0.0007108377,0.004089371,0.0008078111,0.0007216955,0.002011499,0.001233637,0.005668599,0.00112797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001285656,"about_ca_system_score_gemma":0.001168234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003437785,"about_ca_topic_score_gemma":0.00398322,"domain_scores_codex":[0.9978033,0.0008229251,0.0001680655,0.0003514234,0.0003687333,0.0004855258],"domain_scores_gemma":[0.9937392,0.001037374,0.001513595,0.0006151647,0.001008072,0.002086519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7117711,0.02207236,0.1286015,0.0006330091,0.01504921,0.0007160649,0.0008669673,0.003498882,0.006791945,0.0003309113,0.01286357,0.09680451],"study_design_scores_gemma":[0.06835515,0.2943687,0.6080704,0.0001854611,0.01285867,0.0008038654,0.0005620452,0.002714238,0.002353325,0.0007380455,0.008774296,0.0002158355],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803278,0.008089166,0.0008763502,0.001202166,0.0004384691,0.0006886992,0.00497827,0.0001132015,0.003285851],"genre_scores_gemma":[0.9888531,0.001064882,0.0003517523,0.00133038,0.0001638625,0.0003896642,0.005584063,0.00003139924,0.002230866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008208975,"threshold_uncertainty_score":0.04341376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06057921579186873,"score_gpt":0.3349619899212702,"score_spread":0.2743827741294015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}