{"id":"W2903087213","doi":"10.1016/j.jmb.2018.11.021","title":"The Fibrillin-1 RGD Integrin Binding Site Regulates Gene Expression and Cell Function through microRNAs","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; China Scholarship Council; Studienstiftung des Deutschen Volkes; Réseau de Recherche en Santé Buccodentaire et Osseuse; McGill University; Heart and Stroke Foundation of Canada","keywords":"Fibrillin; Fibronectin; Extracellular matrix; Integrin; Cell biology; microRNA; Biology; Cell adhesion; Focal adhesion; Gene expression; Signal transduction; Cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005267051,0.0001322841,0.0002538234,0.0001288702,0.0001615288,0.00003060268,0.000125528,0.0001666217,0.00005753255],"category_scores_gemma":[0.0002100633,0.00007640917,0.0001262171,0.0001443127,0.0003095289,0.00004494096,0.0001390717,0.0003641533,0.0000437463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000476292,"about_ca_system_score_gemma":0.00007839817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007497942,"about_ca_topic_score_gemma":0.000001711946,"domain_scores_codex":[0.9987324,0.0002149692,0.0003888658,0.0001894375,0.0002031391,0.000271121],"domain_scores_gemma":[0.998891,0.0001344823,0.0002682514,0.0002379775,0.0003459779,0.0001223221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006664661,0.00002823143,0.00118687,0.00001482385,0.00004610384,0.00007727908,0.00009116456,0.000001047076,0.9935052,0.00003020339,0.001560325,0.002792296],"study_design_scores_gemma":[0.0009699069,0.001759171,0.0009590138,0.00007698857,0.00004852259,0.0006277975,0.00008172446,0.00002616562,0.952422,0.0005425895,0.04241214,0.00007396947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840884,0.005213607,0.008801685,0.001032291,0.0002659039,0.0001367662,0.000002359187,0.000007444232,0.0004515742],"genre_scores_gemma":[0.9898151,0.001510734,0.007303685,0.0003336183,0.0004037343,0.000001524724,0.000009560282,0.00002465957,0.0005973448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04108318,"threshold_uncertainty_score":0.3115875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01603721417444399,"score_gpt":0.3033192233328747,"score_spread":0.2872820091584307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}