{"id":"W2903087213","doi":"10.1016/j.jmb.2018.11.021","title":"The Fibrillin-1 RGD Integrin Binding Site Regulates Gene Expression and Cell Function through microRNAs","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; China Scholarship Council; Studienstiftung des Deutschen Volkes; Réseau de Recherche en Santé Buccodentaire et Osseuse; McGill University; Heart and Stroke Foundation of Canada","keywords":"Fibrillin; Fibronectin; Extracellular matrix; Integrin; Cell biology; microRNA; Biology; Cell adhesion; Focal adhesion; Gene expression; Signal transduction; Cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002708373,0.0003992883,0.0002849656,0.000303891,0.0004254628,0.0006340952,0.0002785409,0.0004332367,0.001782173],"category_scores_gemma":[0.0003446836,0.0003021406,0.0003745729,0.0001273421,0.0003146737,0.0002922615,0.0003319815,0.001010361,0.0006007485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004882137,"about_ca_system_score_gemma":0.0003069455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007932088,"about_ca_topic_score_gemma":0.001029832,"domain_scores_codex":[0.9996014,0.00007617456,0.00002354585,0.0001203308,0.00007294716,0.0001056014],"domain_scores_gemma":[0.9997929,0.00004737681,0.00006935863,0.00002085358,0.0000340212,0.00003562553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001695098,0.0000135333,0.0004534213,0.00003017441,0.00001072313,0.0001136704,0.00004394083,0.00006764728,0.9952037,0.0009263119,0.0002155324,0.002751851],"study_design_scores_gemma":[0.0001151522,0.00035221,0.02950039,0.0000305342,0.0001077433,0.0006457475,0.0001775858,0.003109235,0.9483719,0.0008082853,0.01675053,0.00003065215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9591292,0.008698242,0.02064423,0.0007514406,0.0004637485,0.00006371895,0.0006466003,0.0004183492,0.00918449],"genre_scores_gemma":[0.9909536,0.0008957424,0.003434302,0.0002625428,0.0000459865,0.00005198192,0.0003075992,0.00007980278,0.003968498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001782173,"threshold_uncertainty_score":0.005961955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01603721417444399,"score_gpt":0.3033192233328747,"score_spread":0.2872820091584307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}