{"id":"W2903210374","doi":"10.4049/jimmunol.198.supp.222.20","title":"Reactive oxygen species modulate immune cell effector function","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Cell biology; Reactive oxygen species; Immune system; Biology; Effector; Carcinogenesis; Oxidative stress; Cytotoxic T cell; Cell; Cell growth; Intracellular; Mitochondrial ROS; T cell; Stimulation; Immunology; Biochemistry; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001900654,0.0002676652,0.000172996,0.0001374605,0.00009780349,0.0003234309,0.0001404496,0.0003059157,0.00133417],"category_scores_gemma":[0.0000998762,0.00006528665,0.0001438481,0.00007789866,0.0001645255,0.0002196574,0.0001549899,0.0003805226,0.000276254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001352903,"about_ca_system_score_gemma":0.00005203676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000059156,"about_ca_topic_score_gemma":0.00006872079,"domain_scores_codex":[0.9998698,0.00003722217,0.000009367262,0.0000160801,0.00002502594,0.00004246569],"domain_scores_gemma":[0.9998962,0.00002269593,0.00002783631,0.00001245625,0.00001620309,0.00002461858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00023578,0.00003850074,0.0004092997,0.00002774334,0.000003739455,0.00003642532,0.000009797434,0.00004067361,0.998126,0.00008319587,0.0000333606,0.0009554956],"study_design_scores_gemma":[0.00002794668,0.0006144994,0.007123461,0.000008439557,0.00001879305,0.000132348,0.00005416991,0.0005428316,0.9897422,0.0001360445,0.001596521,0.000002767426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960634,0.0017176,0.00077494,0.00009706566,0.00003087673,0.0000132827,0.00009152113,0.00002550905,0.001185879],"genre_scores_gemma":[0.9977924,0.0004110764,0.000439455,0.0000435734,0.00001178386,0.000009715503,0.00007883767,0.000004001283,0.001209215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00133417,"threshold_uncertainty_score":0.004463196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206880868403935,"score_gpt":0.2232528195098601,"score_spread":0.2111840108258208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}