{"id":"W2903326024","doi":"10.1172/jci122595","title":"Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Chylomicron; Phosphatidic acid; Biochemistry; Phospholipid; Enterocyte; Biology; Phosphatidylethanolamine; Cell biology; Chemistry; Lipoprotein; Very low-density lipoprotein; Phosphatidylcholine; Cholesterol; Small intestine; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636802,0.000361807,0.0002411355,0.0002668732,0.0002516324,0.0006159653,0.0002408403,0.0003149762,0.0008454484],"category_scores_gemma":[0.0001331733,0.00015931,0.0002603644,0.0001677636,0.0003095404,0.0003574309,0.0004016644,0.0004811869,0.0004546436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005496227,"about_ca_system_score_gemma":0.0004276431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007729263,"about_ca_topic_score_gemma":0.001175253,"domain_scores_codex":[0.9998722,0.00001365818,0.00001079987,0.00003604692,0.00002960813,0.00003763176],"domain_scores_gemma":[0.9999114,0.000006079845,0.00002337146,0.00001284896,0.00001550383,0.00003072549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001439576,0.000007039218,0.0003037041,0.00002496081,0.000003382134,0.00005242847,0.0000103011,0.00004779069,0.9981633,0.0002067696,0.0000493415,0.0009870484],"study_design_scores_gemma":[0.00003201581,0.00008310971,0.008638855,0.000009972362,0.00001860751,0.000284044,0.00004860088,0.001092426,0.9837256,0.0002558673,0.005802627,0.000008186566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767421,0.007033209,0.01098881,0.0003481859,0.0001045216,0.00006175645,0.0008138084,0.0003627846,0.003544841],"genre_scores_gemma":[0.9893707,0.00187832,0.003561683,0.000117015,0.00002165744,0.00005189825,0.0005666423,0.00005485004,0.00437714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008454484,"threshold_uncertainty_score":0.003987849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03310942295819737,"score_gpt":0.3284669026635041,"score_spread":0.2953574797053068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}