{"id":"W2903628113","doi":"10.1016/j.stem.2018.11.005","title":"yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs","year":2018,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Stiftung für Herzforschung; Deutsche Forschungsgemeinschaft; Universität zu Köln; Else Kröner-Fresenius-Stiftung; Stem Cell Network","keywords":"Biology; Brachyury; Mesoderm; Genetics; Cell fate determination; Embryonic stem cell; Cell biology; Gene; Gastrulation; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002077884,0.0003031676,0.0002836645,0.0003818015,0.0004876837,0.0007917348,0.0001985089,0.0003206646,0.002038647],"category_scores_gemma":[0.0002978372,0.0001694125,0.0004734897,0.0002820712,0.0004440349,0.0003358345,0.0004748765,0.0006262419,0.0009840014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004318237,"about_ca_system_score_gemma":0.0006040046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001297098,"about_ca_topic_score_gemma":0.001916991,"domain_scores_codex":[0.9997681,0.00001822835,0.00002711835,0.00009499514,0.00004366176,0.00004794684],"domain_scores_gemma":[0.9997353,0.00003464894,0.00008932412,0.0000296196,0.00004554296,0.00006554516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001457123,0.000007399773,0.001983056,0.00002906061,0.000006599325,0.0001242468,0.00003640633,0.0001210106,0.993501,0.0005032705,0.0001139223,0.003428341],"study_design_scores_gemma":[0.00002819634,0.0001882428,0.02525398,0.00002033837,0.0000362611,0.001004443,0.0001325654,0.00187041,0.9587163,0.0004456236,0.01227559,0.00002813649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612368,0.003121197,0.02824751,0.0002047709,0.0001093051,0.000075442,0.002585693,0.0003833644,0.004035861],"genre_scores_gemma":[0.9864259,0.0005421928,0.006142748,0.0001716088,0.00003632077,0.00004802442,0.0025511,0.0001479919,0.003934124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038647,"threshold_uncertainty_score":0.006819963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307547011179163,"score_gpt":0.2469978675171626,"score_spread":0.2339223974053709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}