{"id":"W2903683006","doi":"10.1111/mmi.14182","title":"Characterization of the <i>Citrobacter rodentium</i> Cpx regulon and its role in host infection","year":2018,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Health and Medical Research Council; Medical Research Council; Canadian Institutes of Health Research; McGill University; Killam Trusts; Michael Smith Health Research BC; University of British Columbia","keywords":"Citrobacter rodentium; DsbA; Biology; Regulon; Microbiology; Bacterial adhesin; Virulence; Chaperone (clinical); Pilus; Pathogen; Effector; Type three secretion system; Secretion; Escherichia coli; Gene; Genetics; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001436646,0.000111538,0.0001294929,0.0000482584,0.0000552589,0.000008132386,0.0001238381,0.0001465179,0.000007474841],"category_scores_gemma":[0.0000871857,0.00008946722,0.00004622497,0.0001491128,0.0001978775,0.000004218136,0.0003061379,0.00008829733,0.000004017621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001282438,"about_ca_system_score_gemma":0.00003163378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002942041,"about_ca_topic_score_gemma":0.0002057205,"domain_scores_codex":[0.9991488,0.0001834751,0.0001628884,0.0002638732,0.00003604119,0.0002048602],"domain_scores_gemma":[0.9995489,0.000004684522,0.00008293232,0.0002171821,0.0001246766,0.00002165765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004317354,0.00003127919,0.01444075,0.00001406351,0.00002775819,6.488883e-7,0.00004841994,5.700156e-7,0.9852187,0.0000463285,0.00002652689,0.0001017645],"study_design_scores_gemma":[0.0002799057,0.0001596169,0.08995177,0.00001396179,0.000007102973,0.00001498614,0.000004698794,0.00001196131,0.9015543,0.00001095139,0.007908101,0.0000825932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987121,0.000360339,0.0001347425,0.0001809768,0.0001140502,0.0002399429,0.00001771969,0.00000463127,0.0002354894],"genre_scores_gemma":[0.9991671,0.0001902824,0.00003241353,0.0002775928,0.00006191841,0.00001955236,0.00005378792,0.00001308337,0.0001842771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08366437,"threshold_uncertainty_score":0.3648367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003960520265964382,"score_gpt":0.2205589547348284,"score_spread":0.216598434468864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}