{"id":"W2903712924","doi":"10.1016/j.jff.2018.12.006","title":"Spent hen-derived ACE inhibitory peptide IWHHT shows antioxidative and anti-inflammatory activities in endothelial cells","year":2018,"lang":"en","type":"article","venue":"Journal of Functional Foods","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hydrolysate; Inflammation; Chemistry; Renin–angiotensin system; Peptide; IC50; Tumor necrosis factor alpha; Oxidative stress; Basal (medicine); Pharmacology; Biochemistry; Endocrinology; Internal medicine; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003895421,0.0001696594,0.0002352265,0.0001078753,0.00008826389,0.00003433821,0.0001036285,0.0001163301,0.00007583766],"category_scores_gemma":[0.00005656299,0.0001421266,0.0001292148,0.0000647099,0.0002715352,0.00003391254,0.00009005792,0.0001860472,0.000004473503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003867099,"about_ca_system_score_gemma":0.0001458084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006768436,"about_ca_topic_score_gemma":0.00003584626,"domain_scores_codex":[0.9988829,0.0001081601,0.0003509969,0.000217611,0.0002502488,0.0001900174],"domain_scores_gemma":[0.9992879,0.00003309967,0.0003046455,0.0001161453,0.0001718619,0.00008633318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005632184,0.00009223984,0.006832805,0.00001169888,0.0001261149,0.00001101015,0.00007441107,0.00003093911,0.9904512,0.0000280619,0.001031243,0.0007470516],"study_design_scores_gemma":[0.0009259404,0.0007971206,0.02989198,0.00004506649,0.00002268797,0.00008884026,0.0002908996,0.00001728907,0.9566631,0.00008387087,0.01100928,0.0001638863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997562,0.0004500223,0.0007900781,0.0001216586,0.0004638083,0.0001033392,0.00002265175,0.000003307326,0.0004831321],"genre_scores_gemma":[0.9968278,0.0002490752,0.0006237142,0.0001290081,0.00176003,0.000004001309,0.000005435004,0.00001486186,0.0003860605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03378807,"threshold_uncertainty_score":0.5795757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01142140706781778,"score_gpt":0.2336236021413459,"score_spread":0.2222021950735281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}