{"id":"W2903760315","doi":"10.1111/1753-0407.12881","title":"Combined effect of GABA and glucagon‐like peptide‐1 receptor agonist on cytokine‐induced apoptosis in pancreatic β‐cell line and isolated human islets","year":2018,"lang":"en","type":"article","venue":"Journal of Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Natural Science Foundation of China; Juvenile Diabetes Research Foundation International","keywords":"Pancreatic islets; Endocrinology; Agonist; Internal medicine; Apoptosis; Cytokine; Medicine; Receptor; Glucagon-like peptide-1; Dipeptidyl peptidase-4; Islet; Pharmacology; Diabetes mellitus; Biology; Type 2 diabetes; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006622774,0.0002507791,0.0009775723,0.0003933447,0.00007891527,0.00002942004,0.00007442055,0.0001373044,0.0001166339],"category_scores_gemma":[0.0005191518,0.000182149,0.0001140528,0.0002610578,0.0001770527,0.0001058876,0.00002684057,0.0003080615,0.000009477109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005401767,"about_ca_system_score_gemma":0.00004522556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001500339,"about_ca_topic_score_gemma":0.000001235221,"domain_scores_codex":[0.9983805,0.0001706403,0.0006904187,0.0001990558,0.0002792009,0.0002801776],"domain_scores_gemma":[0.9982877,0.0006117054,0.0004657082,0.0001945256,0.00020691,0.0002334031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006460817,0.000258308,0.1621849,0.0003232987,0.0001528016,0.000003097003,0.0001976038,4.421969e-7,0.8345729,0.000005442572,0.0009536715,0.0007014453],"study_design_scores_gemma":[0.008855835,0.02348045,0.06067938,0.001223642,0.000400108,0.000005610923,0.00009995075,0.000183138,0.9046903,0.00003620524,0.000175551,0.0001698136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974587,0.0003603713,0.000001913787,0.0002982906,0.0002222243,0.0002709036,0.00000824224,0.00001569399,0.001363636],"genre_scores_gemma":[0.9989366,0.00006720584,0.0001941182,0.0003020838,0.0002221911,0.000005566178,0.000008840112,0.00002814524,0.0002352723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1015055,"threshold_uncertainty_score":0.742782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01120791827268968,"score_gpt":0.2561435678149289,"score_spread":0.2449356495422392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}