{"id":"W2903797156","doi":"10.3390/cancers10120524","title":"BRCA Mutations and Breast Cancer Prevention","year":2018,"lang":"en","type":"review","venue":"Cancers","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"","keywords":"Breast cancer; Medicine; Mammography; BRCA mutation; Cancer; Oncology; Mastectomy; Prophylactic Mastectomy; Mutation; Gynecology; Internal medicine; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006335865,0.0005343339,0.0008361645,0.00208036,0.0002456684,0.0008601885,0.0007208405,0.001103515,0.003774249],"category_scores_gemma":[0.001758126,0.0001839336,0.000502089,0.001412932,0.0004185037,0.0007418349,0.0005941143,0.001388505,0.001218218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005241722,"about_ca_system_score_gemma":0.001017998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001341272,"about_ca_topic_score_gemma":0.001750413,"domain_scores_codex":[0.9997271,0.00007367223,0.00003866395,0.00004581454,0.00009041673,0.00002437115],"domain_scores_gemma":[0.9994888,0.0003319571,0.00006150475,0.00001519463,0.00007672515,0.00002580851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00006335574,0.00007223161,0.0005346593,0.0168804,0.0001245509,0.0002524362,0.00006721499,0.0003173351,0.0005176721,0.00498147,0.0241514,0.9520373],"study_design_scores_gemma":[0.00001647982,0.00007771175,0.001973498,0.01234296,0.0001818858,0.002790978,0.00008769297,0.00007456693,0.0004163434,0.003980128,0.9780416,0.00001613603],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008191764,0.9988502,0.00004997225,0.0003102057,0.00009765448,0.000002091677,0.00001325281,0.000003399653,0.0005911997],"genre_scores_gemma":[0.001012004,0.9983035,0.00008560221,0.0001671327,0.0001314447,0.000003482789,0.00002350353,8.724762e-7,0.0002724034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003774249,"threshold_uncertainty_score":0.01262617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02911586079589584,"score_gpt":0.3567508685642909,"score_spread":0.327635007768395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}