{"id":"W2903911519","doi":"10.1126/sciimmunol.aav4036","title":"Generation and molecular recognition of melanoma-associated antigen-specific human γδ T cells","year":2018,"lang":"en","type":"article","venue":"Science Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Sunnybrook Hospital","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Krembil Foundation","keywords":"Antigen; Biology; Major histocompatibility complex; Immunology; Peptide; Melanoma; Cancer research; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468562,0.0002543755,0.0001370124,0.0001588553,0.0001042387,0.0002482209,0.0001714152,0.0002092914,0.000761946],"category_scores_gemma":[0.0001300822,0.000154441,0.0001861407,0.0001252966,0.00009269271,0.00010401,0.0001893384,0.0005908459,0.0004064762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001113296,"about_ca_system_score_gemma":0.0001281595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001600413,"about_ca_topic_score_gemma":0.0001688624,"domain_scores_codex":[0.999878,0.00002567531,0.00001477823,0.00002718254,0.00003117998,0.00002307705],"domain_scores_gemma":[0.9999586,0.000005949462,0.000005783163,0.00001385536,0.000006661702,0.000009040831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004743611,0.00003424015,0.0001699957,0.00002659273,0.000003180929,0.00004914737,0.00003381243,0.0001833735,0.9964563,0.0002350807,0.00005539554,0.002705395],"study_design_scores_gemma":[0.00003938097,0.0003923941,0.001284609,0.000011317,0.00001786857,0.0004904648,0.00003262058,0.001329051,0.9902737,0.000178901,0.005945563,0.000004212398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764394,0.001454543,0.01795486,0.0001047723,0.00008289255,0.000254239,0.0003213974,0.00007555143,0.003312399],"genre_scores_gemma":[0.9849296,0.001166198,0.01049151,0.00006636427,0.00001729777,0.00008158097,0.0006323523,0.00001631464,0.00259885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000761946,"threshold_uncertainty_score":0.002548993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856520094113055,"score_gpt":0.2567523913071236,"score_spread":0.228187190365993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}