{"id":"W2903916942","doi":"10.1111/imr.12724","title":"Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis","year":2018,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"Periodontitis; Leukocyte adhesion deficiency; Leukocyte extravasation; Aggressive periodontitis; Inflammation; Biology; Immunology; Extravasation; Mendelian inheritance; Gingivitis; Connective tissue; Pathology; Medicine; Genetics; Gene; Immune system; Dentistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004364527,0.0004429179,0.001708968,0.00005505795,0.00009165823,0.00003115944,0.0008297308,0.0004698074,0.0000566597],"category_scores_gemma":[0.0001774164,0.000238186,0.0006613319,0.0002560152,0.0004471498,0.000004410786,0.0004605181,0.0002736284,0.0001004141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003045897,"about_ca_system_score_gemma":0.0001364117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005205959,"about_ca_topic_score_gemma":0.00001213881,"domain_scores_codex":[0.9974447,0.0005444763,0.0009867562,0.0005342984,0.0001343152,0.0003553911],"domain_scores_gemma":[0.9984493,0.00003471238,0.0005466314,0.0008925982,0.00004857296,0.00002813617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001133069,0.0001915335,0.000006213245,0.001110973,0.00009465962,0.00000316344,0.00001551131,4.088507e-8,0.001151557,0.00004880104,0.0001755301,0.9971907],"study_design_scores_gemma":[0.0001884561,0.0004005735,0.00008110478,0.001782877,0.0002317068,0.0000333249,0.00001214649,3.865404e-8,0.0002100732,0.00004672946,0.9967774,0.0002355834],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006210529,0.9961691,0.000005086375,0.00001560415,0.0001416242,0.001308079,0.00003991856,0.000006299341,0.001693169],"genre_scores_gemma":[0.0002203623,0.9985072,0.0001454828,0.0000457773,0.00009938763,0.0003063987,0.0002770872,0.00002762051,0.000370702],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9969551,"threshold_uncertainty_score":0.9712943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.022912188738634,"score_gpt":0.3081515079620925,"score_spread":0.2852393192234585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}